In spike-timing-dependent plasticity (STDP), the order and precise temporal interval
between presynaptic and postsynaptic spikes determine the sign and magnitude of long …

Spike-timing-dependent synaptic plasticity (STDP) is a leading cellular model for behavioral
learning and memory with rich computational properties. However, the relationship between …

What happens in our brain when we make a decision? What triggers a neuron to send out a
signal? What is the neural code? This textbook for advanced undergraduate and beginning …

Knowing where we are, where we have been, and where we are going is critical to many
behaviors, including navigation and memory. One potential neuronal mechanism underlying …

In the mammalian central nervous system, reactive oxygen species (ROS) generation is
counterbalanced by antioxidant defenses. When large amounts of ROS accumulate …

In cultures of dissociated rat hippocampal neurons, persistent potentiation and depression of
glutamatergic synapses were induced by correlated spiking of presynaptic and postsynaptic …

Neurons in the brain communicate by short electrical pulses, the so-called action potentials
or spikes. How can we understand the process of spike generation? How can we …

Endocannabinoids (eCBs) exert major control over neuronal activity by activating
cannabinoid receptors (CBRs). The functionality of the eCB system is primarily ascribed to …

Hebbian models of development and learning require both activity-dependent synaptic
plasticity and a mechanism that induces competition between different synapses. One form …

Synaptic plasticity provides the basis for most models of learning, memory and development
in neural circuits. To generate realistic results, synapse-specific Hebbian forms of plasticity …