Outwitting an old neglected nemesis: a review on leveraging integrated data-driven approaches to aid in unraveling of leishmanicides of therapeutic potential

SK Kwofie, E Broni, B Dankwa… - Current Topics in …, 2020 - ingentaconnect.com
The global prevalence of leishmaniasis has increased with skyrocketed mortality in the past
decade. The causative agent of leishmaniasis is Leishmania species, which infects …

Molecular docking studies of chloroquine and its derivatives against P23pro‐zbd domain of chikungunya virus: Implication in designing of novel therapeutic strategies

M Kumar, RK Topno, MR Dikhit… - Journal of cellular …, 2019 - Wiley Online Library
The arthropod‐transmitted chikungunya virus has emerged as an epidemic menace that
causes debilitating polyarthritis. With this life‐threatening impact on humans, the possible …

In silico prediction of Glabridin potency against Human Tyrosinase in hyperpigmentation condition

A Kumari - Arti Kumari, Maneesh kumar, Ganesh Chandra Sahoo …, 2021 - papers.ssrn.com
Hyperpigmentation causes aesthetic problems and may lead to cancer. Kojic acid and other
chemicals are used to treat skin conditions, such as sunburn damage, skin patches, scars …

Early diagnostic marker for the conversion of asymptomatic to symptomatic visceral leishmaniasis.

RK Topno, R Kumar, K Pandey… - Journal of Medical …, 2019 - search.ebscohost.com
The study was carried out on 1104 people of visceral leishmaniasis (VL) endemic region to
detect the suitable marker in asymptomatic individuals that illustrate as a marker for …

In silico targeting methylerythritol phosphate pathway IspD enzyme of Mycobacterium tuberculosis for novel anti-mycobacterial drug discovery

P Kumar, M Kumar, H Kumar, S Rana… - Journal of Applied …, 2020 - japsonline.com
The incidence of drug-resistant tuberculosis (TB) is the biggest challenge for the global TB
control. Currently, resistance has been detected for almost all key anti-TB drugs. Therefore …