Early-life adversity and neurological disease: age-old questions and novel answers

AK Short, TZ Baram - Nature Reviews Neurology, 2019 - nature.com
Neurological illnesses, including cognitive impairment, memory decline and dementia, affect
over 50 million people worldwide, imposing a substantial burden on individuals and society …

Early Life Stress Affects Bdnf Regulation: A Role for Exercise Interventions

TS Campbell, KM Donoghue, U Ghosh… - International Journal of …, 2022 - mdpi.com
Early life stress (ELS) encompasses exposure to aversive experiences during early
development, such as neglect or maltreatment. Animal and human studies indicate that ELS …

Levels of physical activity at age 10 years and brain morphology changes from ages 10 to 14 years

F Estévez-López, L Dall'Aglio… - JAMA Network …, 2023 - jamanetwork.com
Importance Physical activity may promote healthy brain development in children, but
previous research was predominantly cross-sectional and included small samples …

Effects of short environmental enrichment on early‐life adversity induced cognitive alternations in adolescent rats

S Joushi, K Esmaeilpour… - Journal of …, 2021 - Wiley Online Library
Early‐life experiences, including parental care, affect cognitive performance later in life.
Being exposed to early‐life maternal separation (MS) increases susceptibility to stress …

[HTML][HTML] The role of maternal exercise on placental, behavioral and genetic alterations induced by prenatal stress

C Luft, MS da Costa, GL Antunes, JR de Oliveira… - Neurochemistry …, 2022 - Elsevier
The present study aimed to evaluate the effects of treadmill maternal exercise on alterations
induced by prenatal stress in neonatal mice. Female and male Balb/c mice were divided into …

Protective and therapeutic effects of exercise on stress-induced memory impairment

PD Loprinzi, E Frith - The journal of physiological sciences, 2019 - Springer
The objective of this paper was to systematically evaluate the potential preventive and
therapeutic effects of exercise in attenuating stress-induced memory impairment. A …

Intranasal oxytocin administration facilitates the induction of long-term potentiation and promotes cognitive performance of maternally separated rats

S Joushi, K Esmaeilpour, Y Masoumi-Ardakani… - …, 2021 - Elsevier
Maternal separation (MS) is known to induce permanent changes in the central nervous
system and is associated with increased levels of anxiety and cognitive impairments. The …

Effects of early life adversities upon memory processes and cognition in rodent models

J Alves, N de Sá Couto-Pereira, RMS de Lima… - Neuroscience, 2022 - Elsevier
Exposure to stressors in early postnatal life induces long-lasting modifications in brain
function. This plasticity, an essential characteristic of the brain that enables adaptation to the …

Choline chloride modulates learning, memory, and synaptic plasticity impairments in maternally separated adolescent male rats

S Shahraki, K Esmaeilpour, M Shabani… - International Journal …, 2022 - Wiley Online Library
Maternal separation (MS) is a model to induce permanent alternations in the central nervous
system (CNS) and is associated with increased levels of anxiety and cognitive deficiencies …

Adolescent Nonpharmacological Interventions for Early-Life Stress and Their Mechanism

Y Li, DD Shi, Z Wang - Behavioural Brain Research, 2023 - Elsevier
Those with a negative experience of psychosocial stress during the early stage of life not
only have a high susceptibility of the psychiatric disorder in all phases of their life span, but …