Pyrazoline is an important five membered nitrogen heterocycle, which has been extensively
researched upon. The ring is quite stable and has inspired chemists to carry out various …

Monoamine oxidase plays a significant role in the control of intracellular concentration of
monoaminergic neurotransmitters or neuromodulators and dietary amines. The rapid …

As a part of ongoing studies in developing new potent antimicrobial agents, a series of novel
2-(3-pyridyl)-4, 5-disubstituted thiazoles was efficiently synthesized and characterized by …

Depression is currently the fourth leading cause of disease or disability worldwide.
Antidepressant is approved for the treatment of major depression (including paediatric …

In an effort to develop potent antidepressant agents, new pyrazoline derivatives 2a–s were
synthesized and evaluated for their antidepressant-like activity by tail suspension test (TST) …

The present work deals with the synthesis of acetoxysulfonamide pyrazole derivatives,
substituted 4, 5-dihydropyrazole-1-carbothioamide and 4, 5-dihydropyrazole-1-isonicotinoyl …

In the five membered nitrogen containing heterocyclic family, pyrazoline could be
recognized as a promising scaffold for the inhibition of Monoamine oxidase. Substitution at …

Dihydropyrazole, a small bioactive molecule, is a prominent structural motif found in
numerous pharmaceutically active compounds. The chiral dihydropyrazole structure has …

A series of new 2-pyrazoline derivatives (1c–12c) bearing one to twelve carbon homologous
alkyloxy side chains have been synthesized in good to excellent yields via intramolecular …

As nitrogen-containing five-membered heterocyclic structural units, the substituted pyrazole
derivatives have a broad spectrum of pharmacological activities, especially 4, 5-dihydro-1H …