The anticancer properties of silibinin: its molecular mechanism and therapeutic effect in breast cancer
A Binienda, S Ziolkowska… - Anti-Cancer Agents in …, 2020 - ingentaconnect.com
Background: Silibinin (SB), the main component of Silymarin (SM), is a natural substance
obtained from the seeds of the milk thistle. SM contains up to 70% of SB as two isoforms: A …
obtained from the seeds of the milk thistle. SM contains up to 70% of SB as two isoforms: A …
Functional oral nanoparticles for delivering silibinin and cryptotanshinone against breast cancer lung metastasis
Y Liu, X Xie, X Hou, J Shen, J Shi, H Chen, Y He… - Journal of …, 2020 - Springer
Background Breast cancer lung metastasis occurs in more than 60% of all patients with
breast cancer, and most of those afflicted by it eventually die of recurrence. The tumor …
breast cancer, and most of those afflicted by it eventually die of recurrence. The tumor …
Preparation and investigation of indirubin‐loaded SLN nanoparticles and their anti‐cancer effects on human glioblastoma U87MG cells
A Rahiminejad, R Dinarvand, B Johari… - Cell biology …, 2019 - Wiley Online Library
Indirubin, an ingredient in traditional Chinese medicine, is considered as an anti‐cancer
agent. However, due to its hydrophobic nature, clinical efficiency has been limited. Drug …
agent. However, due to its hydrophobic nature, clinical efficiency has been limited. Drug …
Multifunctional nanosystem for targeted and controlled delivery of multiple chemotherapeutic agents for the treatment of drug-resistant breast cancer
By targeting CD44 receptors, inhibiting multidrug resistance (MDR), controlling drug release,
and synergistically inhibiting tumor growth, a multilayered nanosystem was developed to …
and synergistically inhibiting tumor growth, a multilayered nanosystem was developed to …
[HTML][HTML] Silybin suppresses cell proliferation and induces apoptosis of multiple myeloma cells via the PI3K/Akt/mTOR signaling pathway
N Feng, J Luo, X Guo - Molecular Medicine Reports, 2016 - spandidos-publications.com
Silybin is a biologically active component extracted from the seeds of Silybum marianum,
which has been shown to have inhibitory effects on prostate, skin, bladder, lung and colon …
which has been shown to have inhibitory effects on prostate, skin, bladder, lung and colon …
[HTML][HTML] The protection of bisphenol A-modulated miRNAs and targets by natural products
YT Chuang, CY Yen, W Liu, TM Chien, FR Chang… - Environment …, 2025 - Elsevier
Bisphenol A (BPA) is a ubiquitous environmental pollutant with endocrine-disrupting
functions. Identifying protective drugs and exploring the mechanisms against BPA are …
functions. Identifying protective drugs and exploring the mechanisms against BPA are …
Formulation and evaluation of targeted nanoparticles for breast cancer theranostic system
Theranostic polymeric NPs developed for both cancer diagnosis and cancer therapy. This
multifunctional polymeric vehicle was prepared by a single emulsion evaporation method …
multifunctional polymeric vehicle was prepared by a single emulsion evaporation method …
Silymarin inhibited DU145 cells by activating SLIT2 protein and suppressing expression of CXCR4
Among other cancers, prostate cancer is globally the second most rampant one with the
incidence of 29.4% among men. SLIT2/ROBO1 signaling is very crucial pathway causally …
incidence of 29.4% among men. SLIT2/ROBO1 signaling is very crucial pathway causally …
Phyto-phospholipid complexation as a novel drug delivery system for management of cancer with better bioavailability: current perspectives and future prospects
RK Sahu, WM Aboulthana… - Anti-Cancer Agents in …, 2021 - ingentaconnect.com
Cancer is the foremost cause of death, and it supports the need for the identification of novel
anticancer drugs to improve the efficacy of current-therapy. While the synthetic anticancer …
anticancer drugs to improve the efficacy of current-therapy. While the synthetic anticancer …