Phase I and II drug metabolizing enzymes (DME) and drug transporters are involved in the
absorption, distribution, metabolism as well as elimination of many therapeutic agents …

As one of the main extra‐hepatic cytochrome P450 (CYP) enzymes, CYP1A1 has been
comprehensively investigated for its ability to metabolize both exogenous and endogenous …

Eicosanoids are a class of functionally bioactive lipid mediators derived from the metabolism
of long-chain polyunsaturated fatty acids (PUFAs) mediated by multiple enzymes of three …

Abstract Cytochrome P450 1A1 (CYP1A1) usually metabolizes carcinogens to their inactive
derivatives but occasionally converts the chemicals to more potent carcinogens. To date …

CYP1A1 is an important xenobiotic metabolizing enzyme, present in liver and kidney.
Expression of CYP1A1 enzyme increases manifold when kidney cells are exposed to …

The results from the published studies on the relationship between GSTM1/GSTT1 null
genotypes and renal cell carcinoma (RCC) risk are still conflicting. This meta-analysis was …

Polycyclic aromatic hydrocarbons (PAHs) are carcinogenic compounds which are emitted
through incomplete combustion of organic materials, fossil fuels, consumption of processed …

In first part of this study, a systematic review was designed to explore the involvement of
CYP1A1 and GSTP1 genes in breast cancerogenesis. Based on systematic review, we …

Abstract Background Cytochrome P450 2D6 (CYP2D6) allelic distribution exhibits
differences amongst worldwide populations. There is lack of data from Mumbai, Western …

The current study examined the relationship between renal cell carcinoma-related risk and
gene polymorphisms in the interleukin-10, vitamin D receptor and cytochrome P450 1A1 …