Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages
The COVID-19 pandemic caused by infection with SARS-CoV-2 has led to more than
200,000 deaths worldwide. Several studies have now established that the …
200,000 deaths worldwide. Several studies have now established that the …
The trinity of COVID-19: immunity, inflammation and intervention
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …
Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19
T Herold, V Jurinovic, C Arnreich, BJ Lipworth… - Journal of Allergy and …, 2020 - Elsevier
Background Coronavirus disease 2019 (COVID-19) can manifest as a viral-induced
hyperinflammation with multiorgan involvement. Such patients often experience rapid …
hyperinflammation with multiorgan involvement. Such patients often experience rapid …
SARS-CoV-2: a storm is raging
SF Pedersen, YC Ho - The Journal of clinical investigation, 2020 - Am Soc Clin Investig
The pandemic coronavirus infectious disease (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is rapidly spreading across the globe. In …
respiratory syndrome coronavirus 2 (SARS-CoV-2), is rapidly spreading across the globe. In …
Immune response, inflammation, and the clinical spectrum of COVID-19
LF García - Frontiers in immunology, 2020 - frontiersin.org
The current COVID-19 pandemic began in December 2019 in Wuhan (China) and rapidly
extended to become a global sanitary and economic emergency. Its etiological agent is the …
extended to become a global sanitary and economic emergency. Its etiological agent is the …
Cytokine storm and leukocyte changes in mild versus severe SARS-CoV-2 infection: Review of 3939 COVID-19 patients in China and emerging pathogenesis and …
Clinical evidence indicates that the fatal outcome observed with severe acute respiratory
syndrome-coronavirus-2 infection often results from alveolar injury that impedes airway …
syndrome-coronavirus-2 infection often results from alveolar injury that impedes airway …
Host-viral infection maps reveal signatures of severe COVID-19 patients
Viruses are a constant threat to global health as highlighted by the current COVID-19
pandemic. Currently, lack of data underlying how the human host interacts with viruses …
pandemic. Currently, lack of data underlying how the human host interacts with viruses …
[HTML][HTML] SARS-CoV-2 spike protein S1 subunit induces pro-inflammatory responses via toll-like receptor 4 signaling in murine and human macrophages
K Shirato, T Kizaki - Heliyon, 2021 - cell.com
Abstract Coronavirus disease 2019 (COVID-19), an infectious disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has now spread globally. Some …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has now spread globally. Some …
Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition: an expert opinion
PE Verweij, BJA Rijnders, RJM Brüggemann… - Intensive care …, 2020 - Springer
Purpose Invasive pulmonary aspergillosis is increasingly reported in patients with influenza
admitted to the intensive care unit (ICU). Classification of patients with influenza-associated …
admitted to the intensive care unit (ICU). Classification of patients with influenza-associated …
[HTML][HTML] Devilishly radical NETwork in COVID-19: Oxidative stress, neutrophil extracellular traps (NETs), and T cell suppression
G Schönrich, MJ Raftery, Y Samstag - Advances in biological regulation, 2020 - Elsevier
Abstract Pandemic coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …