Microbial biofilm: a review on formation, infection, antibiotic resistance, control measures, and innovative treatment

S Sharma, J Mohler, SD Mahajan, SA Schwartz… - Microorganisms, 2023 - mdpi.com
Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide
matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to …

Nanomaterial-based therapeutics for antibiotic-resistant bacterial infections

JMV Makabenta, A Nabawy, CH Li… - Nature Reviews …, 2021 - nature.com
Antibiotic-resistant bacterial infections arising from acquired resistance and/or through
biofilm formation necessitate the development of innovative 'outside of the box'therapeutics …

Antibiotic resistance and persistence—Implications for human health and treatment perspectives

M Huemer, S Mairpady Shambat, SD Brugger… - EMBO …, 2020 - embopress.org
Antimicrobial resistance (AMR) and persistence are associated with an elevated risk of
treatment failure and relapsing infections. They are thus important drivers of increased …

Beyond risk: bacterial biofilms and their regulating approaches

MH Muhammad, AL Idris, X Fan, Y Guo, Y Yu… - Frontiers in …, 2020 - frontiersin.org
Bacterial biofilms are complex surface attached communities of bacteria held together by
self-produced polymer matrixs mainly composed of polysaccharides, secreted proteins, and …

Bacterial biofilm and its role in the pathogenesis of disease

LK Vestby, T Grønseth, R Simm, LL Nesse - Antibiotics, 2020 - mdpi.com
Recognition of the fact that bacterial biofilm may play a role in the pathogenesis of disease
has led to an increased focus on identifying diseases that may be biofilm-related. Biofilm …

Potentiating hypoxic microenvironment for antibiotic activation by photodynamic therapy to combat bacterial biofilm infections

W Xiu, L Wan, K Yang, X Li, L Yuwen, H Dong… - Nature …, 2022 - nature.com
Traditional antibiotic treatment has limited efficacy for the drug-tolerant bacteria present in
biofilms because of their unique metabolic conditions in the biofilm infection …

Andrographis paniculata (Burm. f.) Wall. ex Nees: An Updated Review of Phytochemistry, Antimicrobial Pharmacology, and Clinical Safety and Efficacy

S Hossain, Z Urbi, H Karuniawati, RB Mohiuddin… - Life, 2021 - mdpi.com
Infectious disease (ID) is one of the top-most serious threats to human health globally,
further aggravated by antimicrobial resistance and lack of novel immunization options …

Bacterial biofilm formation on implantable devices and approaches to its treatment and prevention

Z Khatoon, CD McTiernan, EJ Suuronen, TF Mah… - Heliyon, 2018 - cell.com
In living organisms, biofilms are defined as complex communities of bacteria residing within
an exopolysaccharide matrix that adheres to a surface. In the clinic, they are typically the …

Antibacterial carbon dots: mechanisms, design, and applications

WB Zhao, KK Liu, Y Wang, FK Li, R Guo… - Advanced …, 2023 - Wiley Online Library
The increase in antibiotic resistance promotes the situation of developing new antibiotics at
the forefront, while the development of non‐antibiotic pharmaceuticals is equally significant …

Chronic inflammation in non-healing skin wounds and promising natural bioactive compounds treatment

P Schilrreff, U Alexiev - International journal of molecular sciences, 2022 - mdpi.com
Chronic inflammation is one of the hallmarks of chronic wounds and is tightly coupled to
immune regulation. The dysregulation of the immune system leads to continuing …