Recent identification of new selenocysteine-containing proteins has revealed relationships
between the two trace elements selenium (Se) and iodine and the hormone network …

Micronutrients, mostly iodine and selenium, are required for thyroid hormone synthesis and
function. Iodine is an essential component of thyroid hormones and its deficiency is …

Summary 2 billion individuals worldwide have insufficient iodine intake, with those in south
Asia and sub-Saharan Africa particularly affected. Iodine deficiency has many adverse …

This chapter provides an overview of the disorders caused by iodine deficiency. Extensively
referenced, it includes data on dietary sources of iodine, goitrogens, the effects of iodine …

Autoantibodies (Ab) against the thyroid-stimulating hormone receptor (TSHR) are frequently
found in autoimmune thyroid disease (AITD). Autoantibodies to the TSHR (anti-TSHR-Ab) …

Context: Congenital hypothyroidism, the most frequent endocrine congenital disease, can
occur either based on a thyroid hormone biosynthesis defect or can predominantly be due to …

Endemic cretinism has been classified into neurological and myxedematous types. Profound
mental deficiency, deaf-mutism and cerebral diplegia are predominantly found in the former …

Urinary iodone (UI) excretion and sonographically measured thyroid volume were
investigated in 195 subjects living in 6 separate villages in the Casamance region of …

Hypothyroidism is defined as the lack of action of thyroid hormones on target tissues. The
term autoimmune hypothyroidism identifies situations with insufficient thyroid function …

Iodine is a trace element present in the human body in minute amounts (15 to 25 mg),
almost exclusively in the thyroid gland (1). It is an essential component of the thyroid …