Hyperpolarization-activated cyclic nucleotide–gated (HCN) channels are expressed as four
different isoforms (HCN1-4) in the heart and in the central and peripheral nervous systems …

Lopinavir-ritonavir combination is being used for the treatment of SARS-CoV-2 infection. A
low dose of ritonavir is added to other protease inhibitors to take advantage of potent …

Abstract The coronavirus disease-2019 (COVID-19) pandemic has become a major global
health problem. COVID-19 is caused by severe acute respiratory syndrome coronavirus-2 …

Pacemaker cells are the basis of rhythm in the heart. Cardiovascular diseases, and in
particular, arrhythmias are a leading cause of hospital admissions and have been implicated …

In heart failure (HF), the heart cannot pump blood efficiently and is therefore unable to meet
the body's demands of oxygen, and/or there is increased end‐diastolic pressure. Current …

Loss or dysregulation of the normally precise control of heart rate via the autonomic nervous
system plays a critical role during the development and progression of cardiovascular …

Abstract Surgicel®(Ethicon, North Ryde, NSW, Australia) is an absorbable sheet of oxidized
cellulose polyanhydroglucuronic acid polymer used as an hemostatic in cardiovascular and …

A low resting heart rate (HR) would be of great benefit in cardiovascular diseases.
Ivabradine—a novel selective inhibitor of hyperpolarization-activated cyclic nucleotide gated …

In patients with heart failure, increased sympathetic activity is associated with a positive
chronotropic stimulation leading to accelerated resting heart rate. Elevated heart rate (HR) is …

Introduction: Heart failure (HF) has become a global pandemic. Despite recent
developments in both medical and device treatments, HF incidences continues to increase …