Lessons learned 1 year after SARS-CoV-2 emergence leading to COVID-19 pandemic

KKW To, S Sridhar, KHY Chiu, DLL Hung… - Emerging microbes & …, 2021 - Taylor & Francis
Without modern medical management and vaccines, the severity of the Coronavirus
Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome (SARS) …

Current and innovative methods for the diagnosis of COVID‑19 infection

L Falzone, G Gattuso, A Tsatsakis… - International …, 2021 - spandidos-publications.com
Abstract The Coronavirus Disease 2019 (COVID‑19) pandemic has forced the scientific
community to rapidly develop highly reliable diagnostic methods in order to effectively and …

Neutralizing antibodies correlate with protection from SARS-CoV-2 in humans during a fishery vessel outbreak with a high attack rate

A Addetia, KHD Crawford, A Dingens… - Journal of clinical …, 2020 - Am Soc Microbiol
The development of vaccines against SARS-CoV-2 would be greatly facilitated by the
identification of immunological correlates of protection in humans. However, to date, studies …

SARS-CoV-2 accessory proteins ORF7a and ORF3a use distinct mechanisms to down-regulate MHC-I surface expression

N Arshad, M Laurent-Rolle… - Proceedings of the …, 2023 - National Acad Sciences
Major histocompatibility complex class I (MHC-I) molecules, which are dimers of a
glycosylated polymorphic transmembrane heavy chain and the small-protein β2 …

[HTML][HTML] Genetics and genomics of SARS-CoV-2: A review of the literature with the special focus on genetic diversity and SARS-CoV-2 genome detection

A Rahimi, A Mirzazadeh, S Tavakolpour - Genomics, 2021 - Elsevier
The outbreak of 2019-novel coronavirus disease (COVID-19), caused by SARS-CoV-2,
started in late 2019; in a short time, it has spread rapidly all over the world. Although some …

A novel cell culture system modeling the SARS-CoV-2 life cycle

X Ju, Y Zhu, Y Wang, J Li, J Zhang, M Gong… - PLoS …, 2021 - journals.plos.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the global
pandemic of COVID-19. SARS-CoV-2 is classified as a biosafety level-3 (BSL-3) agent …

SARS-CoV-2 ORF6 disrupts bidirectional nucleocytoplasmic transport through interactions with Rae1 and Nup98

A Addetia, NAP Lieberman, Q Phung, TY Hsiang, H Xie… - MBio, 2021 - Am Soc Microbiol
ABSTRACT RNA viruses that replicate in the cytoplasm often disrupt nucleocytoplasmic
transport to preferentially translate their own transcripts and prevent host antiviral responses …

Interferon induction, evasion, and paradoxical roles during SARS‐CoV‐2 infection

C Chiale, TT Greene, EI Zuniga - Immunological Reviews, 2022 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the causative agent of
coronavirus disease 2019 (COVID‐19), has caused millions of deaths in the past two years …

Structural and non-structural proteins in SARS-CoV-2: potential aspects to COVID-19 treatment or prevention of progression of related diseases

S Kakavandi, I Zare, M VaezJalali, M Dadashi… - Cell Communication and …, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is caused by a new member of the
Coronaviridae family known as severe acute respiratory syndrome coronavirus 2 (SARS …

SARS-CoV-2 one year on: evidence for ongoing viral adaptation

TP Peacock, R Penrice-Randal… - Journal of General …, 2021 - microbiologyresearch.org
SARS-CoV-2 is thought to have originated in the human population from a zoonotic spillover
event. Infection in humans results in a variety of outcomes ranging from asymptomatic cases …