[HTML][HTML] Investigation of stabilized amorphous solid dispersions to improve oral olaparib absorption

T Yun, S Lee, S Yun, D Cho, K Bang, K Kim - Pharmaceutics, 2024 - mdpi.com
In this study, we investigated the formulation of stable solid dispersions to enhance the
bioavailability of olaparib (OLA), a therapeutic agent for ovarian cancer and breast cancer …

Development of ropivacaine hydrochloride-loaded dissolving microneedles as a local anesthetic agent: A proof-of-concept

D Ramadon, PR Karn, QK Anjani, MH Kim… - International Journal of …, 2024 - Elsevier
Ropivacaine hydrochloride (RPL) is a local anesthetic agent that has been widely used for
the treatment of pain during or after surgery. However, this drug is only available in …

Mucoadhesive chitosan-poly (lactic-co-glycolic acid) nanoparticles for intranasal delivery of quetiapine–Development & characterization in physiologically relevant 3D …

DG Gadhave, M Quadros, AR Ugale, M Goyal… - International Journal of …, 2024 - Elsevier
Quetiapine hemifumarate (QF) delivery to the CNS via conventional formulations is
challenging due to poor solubility and lower oral bioavailability (9%). Similarly, many other …

Continuously producible aztreonam-loaded inhalable lipid nanoparticles for cystic fibrosis-associated Pseudomonas aeruginosa infections–Development and in-vitro …

G Chauhan, AA Shaik, SS Sawant, R Diwan… - Biomaterials …, 2025 - Elsevier
Cystic fibrosis (CF) is a genetic disorder affecting nearly 105,000 patients worldwide and is
characterized by poor respiratory function due to accumulation of thick mucus in the lungs …

[HTML][HTML] Micronization of ciprofloxacin by the Supercritical Antisolvent (SAS) Technique

F Zahran, P Marzal, HK Ruiz, E Pérez, L Calvo… - The Journal of …, 2025 - Elsevier
Ciprofloxacin is a broad-spectrum antibiotic that is proposed for pulmonary administration. In
this work micronization of ciprofloxacin was performed by the Supercritical Antisolvent …

The Effect of PVP on The Molecular Interaction, Crystallinity, and Morphology of Biopolymer Film: A Review

GCS Girsang, F Khoerunnisa… - Journal of Fibers and …, 2024 - journals.gesociety.org
Blending of biopolymers with other polymers ie PVP (polyvinylpyrrolidone) is expected to
improve the processability and properties of biopolymer-based films. This blending leads to …