Hybrid molecules: The privileged scaffolds for various pharmaceuticals

S Mishra, P Singh - European journal of medicinal chemistry, 2016 - Elsevier
The practice of polypharmacology is not a new concept but the approaches which are being
adopted for administering the two or more drugs together are varied from time to time …

Quinolines and structurally related heterocycles as antimalarials

K Kaur, M Jain, RP Reddy, R Jain - European journal of medicinal …, 2010 - Elsevier
The quinoline scaffold is prevalent in a variety of pharmacologically active synthetic and
natural compounds. The discovery of chloroquine, the most famous drug containing this …

[HTML][HTML] Medicinal plants: a source of anti-parasitic secondary metabolites

M Wink - Molecules, 2012 - mdpi.com
This review summarizes human infections caused by endoparasites, including protozoa,
nematodes, trematodes, and cestodes, which affect more than 30% of the human …

Whole plant extracts versus single compounds for the treatment of malaria: synergy and positive interactions

P Rasoanaivo, CW Wright, ML Willcox, B Gilbert - Malaria journal, 2011 - Springer
Background In traditional medicine whole plants or mixtures of plants are used rather than
isolated compounds. There is evidence that crude plant extracts often have greater in vitro …

Bioactive metabolites from macrofungi: ethnopharmacology, biological activities and chemistry

DD De Silva, S Rapior, E Sudarman, M Stadler, J Xu… - Fungal Diversity, 2013 - Springer
Exploration of natural sources for novel bioactive compounds has been an emerging field of
medicine over the past decades, providing drugs or lead compounds of considerable …

Squalene: A natural triterpene for use in disease management and therapy

LH Reddy, P Couvreur - Advanced drug delivery reviews, 2009 - Elsevier
Squalene is a natural lipid belonging to the terpenoid family and a precursor of cholesterol
biosynthesis. It is synthesized in humans and also in a wide array of organisms and …

A review of the medicinal potentials of plants of the genus Vernonia (Asteraceae)

NJ Toyang, R Verpoorte - Journal of ethnopharmacology, 2013 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: The Vernonia genus has about one thousand
species and members of the genus are widely used as food and medicine. The aim of this …

[PDF][PDF] The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II

TJ Schmidt, SA Khalid, AJ Romanha, TMA Alves… - 2012 - lavierebelle.org
Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …

β-Carboline alkaloid monomers and dimers: Occurrence, structural diversity, and biological activities

J Dai, W Dan, U Schneider, J Wang - European Journal of Medicinal …, 2018 - Elsevier
Abstract β-Carboline alkaloids are a family of natural and synthetic products with great
structural diversity and outstanding biological activities. This review covers critically …

Marine natural products

JW Blunt, BR Copp, MHG Munro, PT Northcote… - Natural product …, 2011 - pubs.rsc.org
Covering: 2009. Previous review: Nat. Prod. Rep., 2010, 27, 165 This review covers the
literature published in 2009 for marine natural products, with 857 citations (588 for the …