Pathological and pharmacological functions of the metabolites of polyunsaturated fatty acids mediated by cyclooxygenases, lipoxygenases, and cytochrome P450s in …
YW Meng, JY Liu - Pharmacology & Therapeutics, 2024 - Elsevier
Oxylipins have garnered increasing attention because they were consistently shown to play
pathological and/or pharmacological roles in the development of multiple cancers. Oxylipins …
pathological and/or pharmacological roles in the development of multiple cancers. Oxylipins …
[HTML][HTML] The deregulation of arachidonic acid metabolism in ovarian cancer
Q Xia, W Gao, J Yang, Z Xing, Z Ji - Frontiers in Oncology, 2024 - ncbi.nlm.nih.gov
Arachidonic acid (AA) is a crucial polyunsaturated fatty acid in the human body, metabolized
through the pathways of COX, LOX, and cytochrome P450 oxidase to generate various …
through the pathways of COX, LOX, and cytochrome P450 oxidase to generate various …
[HTML][HTML] Targeting estrogen metabolism in high-grade serous ovarian cancer shows promise to overcome platinum resistance
N Marolt, R Pavlič, T Kreft, M Gjogorska… - Biomedicine & …, 2024 - Elsevier
The high mortality rate due to chemoresistance in patients with high-grade ovarian cancer
(HGSOC) emphasizes the urgent need to determine optimal treatment strategies for …
(HGSOC) emphasizes the urgent need to determine optimal treatment strategies for …
[HTML][HTML] Decoding the Role of CYP450 Enzymes in Metabolism and Disease: A Comprehensive Review
BH Abdelmonem, NM Abdelaal, EKE Anwer… - …, 2024 - ncbi.nlm.nih.gov
Abstract Cytochrome P450 (CYP450) is a group of enzymes that play an essential role in
Phase I metabolism, with 57 functional genes classified into 18 families in the human …
Phase I metabolism, with 57 functional genes classified into 18 families in the human …
Effects of Tokishakuyakusan, Keishibukuryogan, and Kamishoyosan on the expression and activity of drug-metabolizing enzymes in the liver and small intestine
K Yokoyama, K Tabata, Y Shinozaki, R Saito… - Pharmacological …, 2024 - Elsevier
The mechanisms of action of traditional herbal medicines are being actively researched, but
little information is available regarding the interactions of these agents with concomitant …
little information is available regarding the interactions of these agents with concomitant …