Advances in the sequencing and the analysis of the genomes of both modern and ancient
peoples have facilitated a number of breakthroughs in our understanding of human …

Determination of haplotype phase is becoming increasingly important as we enter the era of
large-scale sequencing because many of its applications, such as imputing low-frequency …

Genetic data often exhibit patterns broadly consistent with'isolation by distance'—a
phenomenon where genetic similarity decays with geographic distance. In a heterogeneous …

Mexico harbors great cultural and ethnic diversity, yet fine-scale patterns of human genome-
wide variation from this region remain largely uncharacterized. We studied genomic …

Genome-wide patterns of homozygosity runs and their variation across individuals provide a
valuable and often untapped resource for studying human genetic diversity and evolutionary …

Loci involved in local adaptation can potentially be identified by an unusual correlation
between allele frequencies and important ecological variables or by extreme allele …

The human genome is characterised by many runs of homozygous genotypes, where
identical haplotypes were inherited from each parent. The length of each run is determined …

There is little information on inbreeding during the critical early years of human existence.
However, given the small founding group sizes and restricted mate choices it seems …

The Caribbean basin is home to some of the most complex interactions in recent history
among previously diverged human populations. Here, we investigate the population genetic …

Parental relatedness of present-day humans varies substantially across the globe, but little
is known about the past. Here we analyze ancient DNA, leveraging that parental relatedness …