TBBPA, TBBPS, and TCBPA disrupt hESC hepatic differentiation and promote the proliferation of differentiated cells partly via up-regulation of the FGF10 signaling …

R Yang, S Liu, X Liang, N Yin, L Jiang, Y Zhang… - Journal of Hazardous …, 2021 - Elsevier
Halogenated flame retardants (HFRs), including Tetrabromobisphenol A (TBBPA),
Tetrabromobisphenol S (TBBPS), and Tetrachlorobisphenol A (TCBPA), are widely applied …

STIL promotes tumorigenesis of bladder cancer by activating PI3K/AKT/mTOR signaling pathway and targeting c-myc

H Yu, L Chen, X Wang, F Tang, Z Wan, H Wang, Q Fu… - Cancers, 2022 - mdpi.com
Simple Summary Currently; there are no reports on the role of STIL in bladder cancer. Using
public databases; we observed that STIL is highly expressed in bladder cancer and is …

miR‐148a‐3p regulates proliferation and apoptosis of idiopathic gingival fibroma by targeting NPTX1

Y Sun, L Xie, X Ren, L Ran, H He, F Kong… - Oral …, 2024 - Wiley Online Library
Objective Idiopathic gingival fibromatosis (IGF) is a rare heterogeneous disease that results
in the progressive and diffuse hyperplasia of gingival tissues. MicroRNAs are implicated in …

NPTX1 inhibits pancreatic cancer cell proliferation and migration and enhances chemotherapy sensitivity by targeting RBM10

J Wu, G Liu, K An, L Shi - Oncology Letters, 2022 - spandidos-publications.com
Pancreatic cancer (PC), one of the deadliest diseases worldwide, has exhibited an
increasing incidence rate in recent years. The present study aimed to explore the biological …

From Fruit Waste to Medical Insight: The Comprehensive Role of Watermelon Rind Extract on Renal Adenocarcinoma Cellular and Transcriptomic Dynamics

CS Reddy, P Natarajan, P Nimmakayala… - International Journal of …, 2023 - mdpi.com
Cancer researchers are fascinated by the chemistry of diverse natural products that show
exciting potential as anticancer agents. In this study, we aimed to investigate the anticancer …

Systems level insights into the impact of airborne exposure on SARS-CoV-2 pathogenesis and COVID-19 outcome–A multi-omics big data study

J Manivannan, L Sundaresan - Gene Reports, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a viral pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) that led to more than 800, 00 deaths and …

Assessment of circulating proteins in thyroid cancer: Proteome-wide Mendelian randomization and colocalization analysis

Q Fan, S Wen, Y Zhang, X Feng, W Zheng, X Liang… - iScience, 2024 - cell.com
The causality between circulating proteins and thyroid cancer (TC) remains unclear. We
employed five large-scale circulating proteomic genome-wide association studies (GWASs) …

High‐dimensional differential networks with sparsity and reduced‐rank

Y Wang, C Wang, B Jiang - Stat, 2024 - Wiley Online Library
Differential network analysis plays a crucial role in capturing nuanced changes in
conditional correlations between two samples. Under the high‐dimensional setting, the …

Micro-RNA193a-3p Inhibits Breast Cancer Cell Driven Growth of Vascular Endothelial Cells by Altering Secretome and Inhibiting Mitogenesis: Transcriptomic and …

G Azzarito, L Kurmann, B Leeners, RK Dubey - Cells, 2022 - mdpi.com
Breast cancer (BC) cell secretome in the tumor microenvironment (TME) facilitates neo-
angiogenesis by promoting vascular endothelial cell (VEC) growth. Drugs that block BC cell …

Genetics-based approach to identify novel genes regulated by the aryl hydrocarbon receptor in mouse liver

A Jurgelewicz, P Dornbos, M Warren… - Toxicological …, 2021 - academic.oup.com
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor in the Per-Arnt-
Sim superfamily of environmental sensors that is linked to several metabolic diseases …