[HTML][HTML] The Effect of CYP2C19* 2 (rs4244285) and CYP17 (rs743572) SNPs on Adriamycin and Paclitaxel based Chemotherapy Outcomes in Breast Cancer Patients

RA Gudur, SJ Bhosale, AK Gudur… - … Pacific Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Background: Cytochrome P450 (CYP) are phase I metabolizing enzymes involved in
detoxification of chemotherapeutic agents. Among the CYP gene family, including CYP1A1 …

Genetic Polymorphisms of DNA Repair Genes and their Influence on Paclitaxel based Chemotherapy Induced Toxicity Reactions in Breast Cancer Patients

KD Datkhile, PN Reur, SR Kale… - Asian Pacific Journal …, 2024 - journal.waocp.org
Background: Systemic chemotherapy constitutes an indispensable component of breast
cancer (BC) management, where therapeutic drug combinations such as anthracyclines …

[PDF][PDF] Influence of (C1236T and C3435T) Polymorphisms of ABCB1 Gene on Chemotherapy Treatment Outcome and Toxicity in Breast Cancer Patients

RA Gudur, SJ Bhosale, AK Gudur… - Asian Pacific Journal …, 2024 - journal.waocp.org
Abstract Background: ATP Binding Cassette Transporters (ABCB1) gene plays an important
role in transport of different metabolites and anticancer drugs across the cell membrane …

Real-World Outcome of Platinum-Based Chemotherapy in Advanced Breast Cancer (ABC): A Retrospective Study from a Tertiary Cancer Center in India

IM Vaikundaraja, M Dhanushkodi… - Indian Journal of …, 2021 - thieme-connect.com
Introduction There is a paucity of data on platinum-based chemotherapy in advanced breast
cancer (ABC) from developing countries like India. Objectives The objectives were to …