The mammalian circadian system is a complex hierarchical temporal network which is organized around an ensemble of uniquely coupled cells comprising the principal circadian …
L Yuniati, B Scheijen, LT van der Meer… - Journal of cellular …, 2019 - Wiley Online Library
Since the identification of B‐cell translocation gene 1 (BTG1) and BTG2 as antiproliferation genes more than two decades ago, their protein products have been implicated in a variety …
HI Im, PJ Kenny - Trends in neurosciences, 2012 - cell.com
MicroRNAs (miRNAs) are small noncoding RNA transcripts expressed throughout the brain that can regulate neuronal gene expression at the post-transcriptional level. Here, we …
C Savvidis, M Koutsilieris - Molecular medicine, 2012 - Springer
Circadian rhythms show universally a 24-h oscillation pattern in metabolic, physiological and behavioral functions of almost all species. This pattern is due to a fundamental …
K Sun, EC Lai - Nature reviews genetics, 2013 - nature.com
Abstract MicroRNAs (miRNAs) are~ 22 nt RNAs that coordinate vast regulatory networks in animals and thereby influence myriad processes. This Review examines evidence that …
A Wanet, A Tacheny, T Arnould… - Nucleic acids …, 2012 - academic.oup.com
During the last two decades, microRNAs (miRNAs) emerged as critical regulators of gene expression. By modulating the expression of numerous target mRNAs mainly at the post …
HKA Wong, T Veremeyko, N Patel… - Human molecular …, 2013 - academic.oup.com
Alzheimer's disease (AD) is a multifactorial and fatal neurodegenerative disorder for which the mechanisms leading to profound neuronal loss are incompletely recognized. MicroRNAs …
The nervous system equips us with capability to adapt to many conditions and circumstances. We rely on an armamentarium of intricately formed neural circuits for many of …
Neurodevelopmental disorders (NDDs) are characterized by aberrant and delayed early-life development of the brain, leading to deficits in language, cognition, motor behaviour and …