Analysis of the Polymorphisms and Expression Levels of the BCL2, BAX and c-MYC Genes in Patients with Ovarian Cancer

PJ Olbromski, A Bogacz, M Bukowska… - International Journal of …, 2023 - mdpi.com
Ovarian cancer (OC) is one of the biggest problems in gynecological oncology and is one of
the most lethal cancers in women worldwide. Most patients with OC are diagnosed at an …

A new synthetic antitumor naphthoquinone induces ROS-mediated apoptosis with activation of the JNK and p38 signaling pathways

PDO de Almeida, GSB Jobim… - Chemico-Biological …, 2021 - Elsevier
Quinones are plant-derived secondary metabolites that present diverse pharmacological
properties, including antibacterial, antifungal, antiviral, anti-inflammatory, antipyretic and …

The protective mechanism of Nigella sativa against diethylnitrosamine‐induced hepatocellular carcinoma through its antioxidant effect and EGFR/ERK1/2 signaling

YR Shahin, NM Elguindy, A Abdel Bary… - Environmental …, 2018 - Wiley Online Library
A wide variety of natural products have powerful chemopreventive effects due to their
antioxidant, antimutagenic, and anti‐inflammatory activities that enable them to arrest cell …

Identification of new molecular biomarkers in ovarian cancer using the gene expression profile

PJ Olbromski, P Pawlik, A Bogacz… - Journal of Clinical …, 2022 - mdpi.com
Ovarian cancer is a common cause of death among women worldwide. The current
diagnostic and prognostic procedures available for the treatment of ovarian cancer are …

[HTML][HTML] Synsepalum dulcificum extracts exhibit cytotoxic activity on human colorectal cancer cells and upregulate c-fos and c-jun early apoptotic gene expression

J Seong, GG Oyong, EC Cabrera - Asian Pacific Journal of …, 2018 - journals.lww.com
Objective: To explore cytotoxicity of Synsepalum dulcificum (S. dulcificum) Daniell
(Sapotaceae) on human colon cancer (HCT-116 and HT-29), human monocytic leukemia …

Ginsenoside Rh2 induces HeLa apoptosis through Upregulating endoplasmic reticulum stress-related and downstream apoptotic gene expression

Y Liu, X Wang, J Qiao, J Wang, L Jiang, C Wang, S Yu… - Molecules, 2022 - mdpi.com
Cervical cancer is a common gynecological malignancy afflicting women all over the world.
Ginsenoside Rh2 (GRh2), especially 20 (S)-GRh2, is a biologically active component in the …

[HTML][HTML] Corrective effect of verbascoside on histomorphological differences and oxidative stress in colon mucosa of rats in which colon ischemia–reperfusion injury …

AN Değer, F Özyiğit, FE Kocak, Z Bayhan… - The Turkish Journal …, 2021 - ncbi.nlm.nih.gov
Background This study aims to show the corrective effect of verbascoside on
histomorphological and biochemical differences in the colon mucosa of rats in which colon …

The c‑Jun signaling pathway has a protective effect on nucleus pulposus cells in patients with intervertebral disc degeneration

M Lei, K Wang, S Li, K Zhao… - Experimental and …, 2020 - spandidos-publications.com
Among a range of diverse clinical symptoms, intervertebral disc degeneration (IDD)
contributes mostly to the onset of lower back pain. The present study aimed to investigate …

RING finger protein 10 attenuates vascular restenosis by inhibiting vascular smooth muscle cell hyperproliferation in vivo and vitro

S Li, G Yu, F Jing, H Chen, A Liu, M Luo, W Huang… - IUBMB …, 2019 - Wiley Online Library
Vascular smooth muscle cell (VSMC) hyperproliferation is the main pathological process in
various cardiovascular diseases, such as vascular restenosis. This process may be …

[HTML][HTML] Temporal changes in Egr-1 and c-fos expression in rat models of myocardial ischemia

LQ Zhai, XJ Guo, Z Li, RF Sun, QQ Jin… - Annals of Palliative …, 2021 - apm.amegroups.org
Background: The pathological diagnosis of sudden cardiac death caused by myocardial
ischemia is a difficult problem. Relevant evidence shows that the expression of Egr-1 and c …