Myocardial fibrosis: emerging target for cardiac molecular imaging and opportunity for image-guided therapy
FM Bengel, J Diekmann, A Hess… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Myocardial fibrosis is a major contributor to the development and progression of heart
failure. Significant progress in the understanding of its pathobiology has led to the …
failure. Significant progress in the understanding of its pathobiology has led to the …
[HTML][HTML] Recent advances in 19Fluorine magnetic resonance imaging with perfluorocarbon emulsions
AH Schmieder, SD Caruthers, J Keupp, SA Wickline… - Engineering, 2015 - Elsevier
The research roots of 19fluorine (19F) magnetic resonance imaging (MRI) date back over 35
years. Over that time span, 1H imaging flourished and was adopted worldwide with an …
years. Over that time span, 1H imaging flourished and was adopted worldwide with an …
[HTML][HTML] Multiparametric MRI to quantify disease and treatment response in mice with myeloproliferative neoplasms
TH Robison, M Solipuram, K Heist, G Amouzandeh… - JCI insight, 2022 - ncbi.nlm.nih.gov
Histopathology, the standard method to assess BM in hematologic malignancies such as
myeloproliferative neoplasms (MPNs), suffers from notable limitations in both research and …
myeloproliferative neoplasms (MPNs), suffers from notable limitations in both research and …
Optimized CEST cardiovascular magnetic resonance for assessment of metabolic activity in the heart
Background Previous studies have linked cardiac dysfunction to loss of metabolites in the
creatine kinase system. Chemical exchange saturation transfer (CEST) is a promising …
creatine kinase system. Chemical exchange saturation transfer (CEST) is a promising …
On‐resonance variable delay multipulse scheme for imaging of fast‐exchanging protons and semisolid macromolecules
Purpose To develop an on‐resonance variable delay multipulse (VDMP) scheme to image
magnetization transfer contrast (MTC) and the chemical exchange saturation transfer …
magnetization transfer contrast (MTC) and the chemical exchange saturation transfer …
Multi-scale imaging of vascular pathologies in cardiovascular disease
Cardiovascular disease entails systemic changes in the vasculature. The endothelial cells
lining the blood vessels are crucial in the pathogenesis of cardiovascular disease. Healthy …
lining the blood vessels are crucial in the pathogenesis of cardiovascular disease. Healthy …
CEST, ASL, and magnetization transfer contrast: How similar pulse sequences detect different phenomena
Chemical exchange saturation transfer (CEST), arterial spin labeling (ASL), and
magnetization transfer contrast (MTC) methods generate different contrasts for MRI …
magnetization transfer contrast (MTC) methods generate different contrasts for MRI …
Characterization of the ultrashort‐TE (UTE) MR collagen signal
AG Siu, A Ramadeen, X Hu, L Morikawa… - NMR in …, 2015 - Wiley Online Library
Although current cardiovascular MR (CMR) techniques for the detection of myocardial
fibrosis have shown promise, they nevertheless depend on gadolinium‐based contrast …
fibrosis have shown promise, they nevertheless depend on gadolinium‐based contrast …
Non-invasive detection of adeno-associated viral gene transfer using a genetically encoded CEST-MRI reporter gene in the murine heart
Research into gene therapy for heart failure has gained renewed interest as a result of
improved safety and availability of adeno-associated viral vectors (AAV). While magnetic …
improved safety and availability of adeno-associated viral vectors (AAV). While magnetic …
Multimodal assessment of orbital immune cell infiltration and tissue remodeling during development of graves disease by 1H19F MRI
U Flögel, A Schlüter, C Jacoby… - Magnetic …, 2018 - Wiley Online Library
Purpose To evaluate key molecular and cellular features of Graves orbitopathy (GO) by
simultaneous monitoring of alterations in morphology, inflammatory patterns, and tissue …
simultaneous monitoring of alterations in morphology, inflammatory patterns, and tissue …