PC Vioglio, MR Chierotti, R Gobetto - Advanced Drug Delivery Reviews, 2017 - Elsevier
In recent years many efforts have been devoted to the screening and the study of new solid- state forms of old active pharmaceutical ingredients (APIs) with salification or co …
M Li, W Xu, Y Su - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
Solid-state NMR (ssNMR) spectroscopy analyzes a wide range of pharmaceutical materials in a non-disruptive and non-invasive manner. The obtained molecular properties at …
Due to their strong dependence on local atonic environments, NMR chemical shifts are among the most powerful tools for strucutre elucidation of powdered solids or amorphous …
D Tan, T Friščić - European Journal of Organic Chemistry, 2018 - Wiley Online Library
We provide a brief overview of recent advances in the use of mechanochemical techniques for the synthesis of organic molecules and materials, highlighting selected examples of …
P Hodgkinson - Progress in Nuclear Magnetic Resonance …, 2020 - Elsevier
Developments of NMR methodology to characterise the structures of molecular organic structures are reviewed, concentrating on the previous decade of research in which density …
M Solares-Briones, G Coyote-Dotor, JC Páez-Franco… - Pharmaceutics, 2021 - mdpi.com
Mechanochemistry is considered an alternative attractive greener approach to prepare diverse molecular compounds and has become an important synthetic tool in different fields …
E Pindelska, A Sokal, W Kolodziejski - Advanced drug delivery reviews, 2017 - Elsevier
The main goal of a novel drug development is to obtain it with optimal physiochemical, pharmaceutical and biological properties. Pharmaceutical companies and scientists modify …
D Wang, Z Yang, B Zhu, X Mei, X Luo - Crystal Growth & Design, 2020 - ACS Publications
A machine-learning model trained on the whole Cambridge Structural Database was developed to assist high-throughput cocrystal screening. With only 2D structures taken as …
A growing number of co‐crystals in the literature are proof of how significant the co‐ crystallization concept has become. Co‐crystallization enhances physicochemical …