[HTML][HTML] The role of connexins in controlling cell growth and gene expression

E Kardami, X Dang, DA Iacobas, BE Nickel… - Progress in biophysics …, 2007 - Elsevier
The purpose of this paper is to provide a brief overview of current thinking on the role of
connexins, in particular Cx43, in growth regulation, and a more detailed discussion as to …

Glial connexins and gap junctions in CNS inflammation and disease

T Kielian - Journal of neurochemistry, 2008 - Wiley Online Library
Gap junctions facilitate direct cytoplasmic communication between neighboring cells,
facilitating the transfer of small molecular weight molecules involved in cell signaling and …

Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host

J Jäderstad, LM Jäderstad, J Li… - Proceedings of the …, 2010 - National Acad Sciences
How grafted neural stem cells (NSCs) and their progeny integrate into recipient brain tissue
and functionally interact with host cells is as yet unanswered. We report that, in organotypic …

[HTML][HTML] Channel-independent influence of connexin 43 on cell migration

P Kameritsch, K Pogoda, U Pohl - Biochimica et Biophysica Acta (BBA) …, 2012 - Elsevier
In this review we focus on the role of connexins, especially of Cx43, as modulators of
migration—a fundamental process in embryogenesis and in physiologic functions of the …

Islet‐cell‐to‐cell communication as basis for normal insulin secretion

S Bavamian, P Klee, A Britan… - Diabetes, Obesity …, 2007 - Wiley Online Library
The emergence of pancreatic islets has necessitated the development of a signalling system
for the intra‐and inter‐islet coordination of β cells. With evolution, this system has evolved …

[HTML][HTML] Gap junctional communication in morphogenesis

M Levin - Progress in biophysics and molecular biology, 2007 - Elsevier
Gap junctions permit the direct passage of small molecules from the cytosol of one cell to
that of its neighbor, and thus form a system of cell–cell communication that exists alongside …

[HTML][HTML] Connexin40 regulates renin production and blood pressure

N Krattinger, A Capponi, L Mazzolai, JF Aubert… - Kidney international, 2007 - Elsevier
Renin secretion is regulated by coordinated signaling between the various cells of the
juxtaglomerular apparatus. The renin-secreting cells (RSC), which play a major role in the …

Genomic Fabrics of the Excretory System's Functional Pathways Remodeled in Clear Cell Renal Cell Carcinoma

DA Iacobas, EA Obiomon, S Iacobas - Current Issues in Molecular …, 2023 - mdpi.com
Clear cell renal cell carcinoma (ccRCC) is the most frequent form of kidney cancer.
Metastatic stages of ccRCC reduce the five-year survival rate to 15%. In this report, we …

Coordinated activity of transcriptional networks responding to the pattern of action potential firing in neurons

DA Iacobas, S Iacobas, PR Lee, JE Cohen, RD Fields - Genes, 2019 - mdpi.com
Transcriptional responses to the appropriate temporal pattern of action potential firing are
essential for long-term adaption of neuronal properties to the functional activity of neural …

[HTML][HTML] Gene master regulators of papillary and anaplastic thyroid cancers

DA Iacobas, NY Tuli, S Iacobas, JK Rasamny… - Oncotarget, 2018 - ncbi.nlm.nih.gov
We hypothesize that distinct cell phenotypes are governed by different sets of gene master
regulators (GMRs) whose strongly protected (by the homeostatic mechanisms) abundance …