Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Traumatic brain injury (TBI) remains one of the most fatal and debilitating conditions in the
world. Current clinical management in severe TBI patients is mainly concerned with …

Background Traumatic brain injury (TBI) is increasingly recognised as being responsible for
a substantial proportion of the global burden of disease. Neurosurgical interventions are an …

Background Alternative noninvasive methods capable of excluding intracranial hypertension
through use of transcranial Doppler (ICP tcd) in situations where invasive methods cannot …

Importance While the relationship between persistent elevations in intracranial pressure
(ICP) and poorer outcomes is well established for patients with traumatic brain injury (TBI) …

Background Optimisation of brain oxygenation might improve neurological outcome after
traumatic brain injury. The OXY-TC trial explored the superiority of a strategy combining …

Abstract Analysis of intracranial pressure waveforms (ICPW) provides information on
intracranial compliance. We aimed to assess the correlation between noninvasive ICPW …

Background: We validated a new noninvasive tool (B4C) to assess intracranial pressure
waveform (ICPW) morphology in a set of neurocritical patients, correlating the data with …

Intensive care for patients with traumatic brain injury (TBI) aims to optimize intracranial
pressure (ICP) and cerebral perfusion pressure (CPP). The transformation of ICP and CPP …

The evolution of intracranial pressure (ICP) of critically ill patients admitted to a
neurointensive care unit (ICU) is difficult to predict. Besides the underlying disease and …