[HTML][HTML] Toxicity of gold nanoparticles (AuNPs): A review

A Sani, C Cao, D Cui - Biochemistry and biophysics reports, 2021 - Elsevier
Gold nanoparticles are a kind of nanomaterials that have received great interest in field of
biomedicine due to their electrical, mechanical, thermal, chemical and optical properties …

[HTML][HTML] Gold nanoparticles for drug delivery and cancer therapy

S Siddique, JCL Chow - Applied Sciences, 2020 - mdpi.com
Nanomaterials are popularly used in drug delivery, disease diagnosis and therapy. Among a
number of functionalized nanomaterials such as carbon nanotubes, peptide nanostructures …

Rekindling RNAi therapy: materials design requirements for in vivo siRNA delivery

B Kim, JH Park, MJ Sailor - Advanced materials, 2019 - Wiley Online Library
With the recent FDA approval of the first siRNA‐derived therapeutic, RNA interference
(RNAi)‐mediated gene therapy is undergoing a transition from research to the clinical …

The progress and promise of RNA medicine─ an arsenal of targeted treatments

JM Sasso, BJB Ambrose, R Tenchov… - Journal of medicinal …, 2022 - ACS Publications
In the past decade, there has been a shift in research, clinical development, and commercial
activity to exploit the many physiological roles of RNA for use in medicine. With the rapid …

[HTML][HTML] Gene therapy in cancer treatment: why go nano?

C Roma-Rodrigues, L Rivas-García, PV Baptista… - Pharmaceutics, 2020 - mdpi.com
The proposal of gene therapy to tackle cancer development has been instrumental for the
development of novel approaches and strategies to fight this disease, but the efficacy of the …

[HTML][HTML] Recent advances of metal-based nanoparticles in nucleic acid delivery for therapeutic applications

AR Sharma, YH Lee, A Bat-Ulzii… - Journal of …, 2022 - Springer
Recent efforts in designing nanomaterials to deliver potential therapeutics to the targeted
site are overwhelming and palpable. Engineering nanomaterials to deliver biological …

Lymph node-targeting nanovaccines for cancer immunotherapy

Q Wang, Z Wang, X Sun, Q Jiang, B Sun, Z He… - Journal of Controlled …, 2022 - Elsevier
Cancer immunotherapies such as tumor vaccines, chimeric antigen receptor T cells and
immune checkpoint blockades, have attracted tremendous attention. Among them, tumor …

Nanotechnology‐Assisted RNA Delivery: From Nucleic Acid Therapeutics to COVID‐19 Vaccines

C Rinoldi, SS Zargarian, P Nakielski, X Li… - Small …, 2021 - Wiley Online Library
In recent years, the main quest of science has been the pioneering of the groundbreaking
biomedical strategies needed for achieving a personalized medicine. Ribonucleic acids …

Delivering the promise of gene therapy with nanomedicines in treating central nervous system diseases

M Luo, LKC Lee, B Peng, CHJ Choi… - Advanced …, 2022 - Wiley Online Library
Abstract Central Nervous System (CNS) diseases, such as Alzheimer's diseases (AD),
Parkinson's Diseases (PD), brain tumors, Huntington's disease (HD), and stroke, still remain …

[HTML][HTML] Non-viral nanoparticles for RNA interference: Principles of design and practical guidelines

Z Liu, S Wang, C Tapeinos, G Torrieri… - Advanced Drug Delivery …, 2021 - Elsevier
Ribonucleic acid interference (RNAi) is an innovative treatment strategy for a myriad of
indications. Non-viral synthetic nanoparticles (NPs) have drawn extensive attention as …