Cancer cells employ an evolutionarily conserved polyploidization program to resist therapy

KJ Pienta, EU Hammarlund, RH Austin… - Seminars in cancer …, 2022 - Elsevier
Unusually large cancer cells with abnormal nuclei have been documented in the cancer
literature since 1858. For more than 100 years, they have been generally disregarded as …

Combining marine macroecology and palaeoecology in understanding biodiversity: microfossils as a model

M Yasuhara, DP Tittensor, H Hillebrand… - Biological …, 2017 - Wiley Online Library
There is growing interest in the integration of macroecology and palaeoecology towards a
better understanding of past, present, and anticipated future biodiversity dynamics …

Cancer recurrence and lethality are enabled by enhanced survival and reversible cell cycle arrest of polyaneuploid cells

KJ Pienta, EU Hammarlund, JS Brown… - Proceedings of the …, 2021 - National Acad Sciences
We present a unifying theory to explain cancer recurrence, therapeutic resistance, and
lethality. The basis of this theory is the formation of simultaneously polyploid and aneuploid …

Ultra-deep sequencing of foraminiferal microbarcodes unveils hidden richness of early monothalamous lineages in deep-sea sediments

B Lecroq, F Lejzerowicz, D Bachar… - Proceedings of the …, 2011 - National Acad Sciences
Deep-sea floors represent one of the largest and most complex ecosystems on Earth but
remain essentially unexplored. The vastness and remoteness of this ecosystem make deep …

Poly‐aneuploid cancer cells promote evolvability, generating lethal cancer

KJ Pienta, EU Hammarlund, R Axelrod… - Evolutionary …, 2020 - Wiley Online Library
Cancer cells utilize the forces of natural selection to evolve evolvability allowing a constant
supply of heritable variation that permits a cancer species to evolutionary track changing …

Benthic foraminiferal biogeography: controls on global distribution patterns in deep-water settings

AJ Gooday, FJ Jorissen - Annual Review of Marine Science, 2012 - annualreviews.org
Benthic foraminifera, shell-bearing protists, are familiar from geological studies. Although
many species are well known, undescribed single-chambered forms are common in the …

Patterns of species richness and the center of diversity in modern Indo-Pacific larger foraminifera

M Förderer, D Rödder, MR Langer - Scientific reports, 2018 - nature.com
Abstract Symbiont-bearing Larger Benthic Foraminifera (LBF) are ubiquitous components of
shallow tropical and subtropical environments and contribute substantially to carbonaceous …

Potential importance of physiologically diverse benthic foraminifera in sedimentary nitrate storage and respiration

JM Bernhard, KL Casciotti, MR McIlvin… - Journal of …, 2012 - Wiley Online Library
Until recently, the process of denitrification (conversion of nitrate or nitrite to gaseous
products) was thought to be performed exclusively by prokaryotes and fungi. The finding that …

Integrated biostratigraphy of the Santonian through Maastrichtian (Upper Cretaceous) of extra-Carpathian Poland

I Walaszczyk, Z Dubicka… - Acta Geologica …, 2016 - geojournals.pgi.gov.pl
The biostratigraphic importance, current zonations, and potential for the recognition of the
standard chronostratigraphic boundaries of five palaeontological groups (benthic …

Benthic foraminifera as environmental indicators in Mediterranean marine caves: A review

E Romano, L Bergamin, M Parise - Geosciences, 2022 - mdpi.com
Marine caves are characterized by wide environmental variability for the interaction between
marine and continental processes. Their conditions may be defined as extreme for …