Age-related changes in aortic biomechanics can impact the brain by reducing blood flow
and increasing pulsatile energy transmission. Clinical studies have shown that impaired …

This study investigates the physics of the longitudinal stretching-based wave pumping
mechanism, a novel extension of the traditional impedance pump. In its simplest form, an …

Aortic stiffness increases with age and is a robust predictor of brain pathology including
Alzheimer's and other dementias. Aging causes disproportionate stiffening of the aorta …

As computational models of the cardiovascular system are applied in modern personalized
medicine, maximizing certainty of model input becomes crucial. A model with a high number …

Abstract Aims Cardiovascular intrinsic frequencies (IFs) are associated with cardiovascular
health and disease, separately capturing the systolic and diastolic information contained in a …

Coarctation of the aorta (CoA) is a congenital disease characterized by the narrowing of the
aorta, typically the descending portion after the left subclavian artery. If left untreated, by the …

Age-related changes in aortic biomechanics can impact the brain by reducing blood flow
and increasing pulsatile energy transmission. Clinical studies have shown that impaired …

Objective To evaluate functional relationship between fetal circulatory response to
intrauterine transfusion (IUT) as a circulatory challenge and appearance of second systolic …

Introduction The wave condition number (WCN) is a non-dimensional number that
determines the state of arterial wave reflections. WCN is equal to HR× L eff/PWV where HR …

In Nature, there exist a variety of cardiovascular circulation networks in which the energetic
ventricular load has both steady and pulsatile components. Steady load is related to the …