Thirty years ago, a novel axis of the renin-angiotensin system (RAS) was unveiled by the
discovery of angiotensin-(1− 7)[ANG-(1− 7)] generation in vivo. Later, angiotensin …

The renin angiotensin system (RAS) regulates fluid balance, blood pressure and maintains
vascular tone. The potent vasoconstrictor angiotensin II (Ang II) produced by angiotensin …

The renin-angiotensin-aldosterone system (RAAS), is an old system with new fundamental
roles in cancer biology which influences cell growth, migration, death, and metastasis. RAAS …

Diminazene aceturate (DIZE), a putative angiotensin-converting enzyme 2 (ACE2) activator,
elicits relaxation in various animal models. This study aimed to determine the relaxing …

Only a few years ago, alamandine was found to be a member of the protective arm of the
renin-angiotensin system. It turned out to be an endogenous ligand of the G protein-coupled …

The development of agricultural products as well as the industrialization of food production
have led to dramatic lifestyle changes, particularly in dietary patterns, which in turn has …

Cardiovascular disease is the major cause of mortality and disability, with hypertension
being the most prevalent risk factor. Excessive activation of the renin-angiotensin system …

Introduction Endothelial damage (ED) has been implicated in accelerating the development
of atherosclerosis. The latter condition is a risk factor for developing several cardiovascular …

The renin-angiotensin system (RAS) is a network of proteins regulating many aspects of
human physiology, including cardiovascular, pulmonary, and immune system physiology …

Aims: The renin–angiotensin system (RAS) plays an important role in the pathophysiology of
vascular diseases, especially as a mediator of inflammation and tissue remodelling …