Cell-matrix interactions play a critical role in tissue repair and regeneration. With gradual
uncovering of substrate mechanical characteristics that can affect cell-matrix interactions …

The clinical translations of drugs and nanomedicines depend on coherent pharmaceutical
research based on biologically accurate screening approaches. Since establishing the 2D in …

Owing to their self‐renewal and differentiation ability, stem cells are conducive for repairing
injured tissues, making them a promising source of seed cells for tissue engineering. The …

The mammalian brain contains few niches for neural stem cells (NSCs) capable of
generating new neurons, whereas other regions are primarily gliogenic. Here we leverage …

Successful tissue regeneration strategies focus on the use of novel biomaterials, structures,
and a variety of cues to control cell behavior and promote regeneration. Studies discovered …

With the lack of minimally invasive tools for probing neuronal systems across spatiotemporal
scales, understanding the working mechanism of the nervous system and limited …

Traumatic brain injury is one of the leading causes of accidental death and disability. The
loss of parts in a severely injured brain induces edema, neuronal apoptosis, and …

The neurovascular unit (NVU), consisting of neurons, glial cells, vascular cells (endothelial
cells, pericytes and vascular smooth muscle cells (VSMCs)) together with the surrounding …

Inflammation is a major pathological event following ischemic stroke that contributes to
secondary brain tissue damage leading to poor functional recovery. Following the initial …

While it is known that mechanical dynamics are influential in neural differentiation for critical
processes like neurogenesis or neurodegeneration, studies on neural stem cell therapies …