Extracellular vesicles and asthma—More than just a co-existence
B Alashkar Alhamwe, DP Potaczek, S Miethe… - International journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) are membranous structures, which are secreted by almost every
cell type analyzed so far. In addition to their importance for cell-cell communication under …
cell type analyzed so far. In addition to their importance for cell-cell communication under …
[HTML][HTML] Specificity of oligonucleotide gene therapy (OGT) agents
DD Nedorezova, MV Dubovichenko, EP Belyaeva… - Theranostics, 2022 - ncbi.nlm.nih.gov
Oligonucleotide gene therapy (OGT) agents (eg antisense, deoxyribozymes, siRNA and
CRISPR/Cas) are promising therapeutic tools. Despite extensive efforts, only few OGT drugs …
CRISPR/Cas) are promising therapeutic tools. Despite extensive efforts, only few OGT drugs …
The role of epigenetics in allergy and asthma development
BA Alhamwe, F Alhamdan, A Ruhl… - Current opinion in …, 2020 - journals.lww.com
The role of epigenetics in allergy and asthma development : Current Opinion in Allergy and
Clinical Immunology The role of epigenetics in allergy and asthma development : Current …
Clinical Immunology The role of epigenetics in allergy and asthma development : Current …
Epigenetic regulation of airway epithelium immune functions in asthma
B Alashkar Alhamwe, S Miethe… - Frontiers in …, 2020 - frontiersin.org
Asthma is a chronic inflammatory disease of the respiratory tract characterized by recurrent
breathing problems resulting from airway obstruction and hyperresponsiveness. Human …
breathing problems resulting from airway obstruction and hyperresponsiveness. Human …
Targeting the pentose phosphate pathway for SARS-CoV-2 therapy
SARS-CoV-2 is causing the coronavirus disease 2019 (COVID-19) pandemic, for which
effective pharmacological therapies are needed. SARS-CoV-2 induces a shift of the host cell …
effective pharmacological therapies are needed. SARS-CoV-2 induces a shift of the host cell …
Respiratory eukaryotic virome expansion and bacteriophage deficiency characterize childhood asthma
S Megremis, B Constantinides, P Xepapadaki… - Scientific Reports, 2023 - nature.com
Asthma development and exacerbation is linked to respiratory virus infections. There is
limited information regarding the presence of viruses during non-exacerbation/infection …
limited information regarding the presence of viruses during non-exacerbation/infection …
Dual role of the miR‐146 family in rhinovirus‐induced airway inflammation and allergic asthma exacerbation
Rhinovirus (RV) infections are associated with asthma exacerbations. MicroRNA‐146a and
microRNA‐146b (miR‐146a/b) are anti‐inflammatory miRNAs that suppress signaling …
microRNA‐146b (miR‐146a/b) are anti‐inflammatory miRNAs that suppress signaling …
How can we minimise the use of regular oral corticosteroids in asthma?
Options to achieve oral corticosteroid (OCS)-sparing have been triggering increasing
interest since the 1970s because of the side-effects of OCSs, and this has now become …
interest since the 1970s because of the side-effects of OCSs, and this has now become …
Deoxyribozymes as catalytic nanotherapeutic agents
LM Khachigian - Cancer research, 2019 - AACR
RNA-cleaving deoxyribozymes (DNAzymes) are synthetic single-stranded DNA-based
catalytic molecules that can be engineered to bind to and cleave target mRNA at …
catalytic molecules that can be engineered to bind to and cleave target mRNA at …
Epigenetic mechanisms in allergy development and prevention
DP Potaczek, B Alashkar Alhamwe, S Miethe… - Allergic diseases–from …, 2021 - Springer
There has been a substantial increase in the incidence and the prevalence of allergic
disorders in the recent decades, which seems to be related to rapid environmental and …
disorders in the recent decades, which seems to be related to rapid environmental and …