[HTML][HTML] Mechanistic Insights and Therapeutic Strategies in Osteoporosis: A Comprehensive Review

NR Elahmer, SK Wong, N Mohamed, E Alias, KY Chin… - Biomedicines, 2024 - mdpi.com
Osteoporosis, a metabolic bone disorder characterized by decreased bone mass per unit
volume, poses a significant global health burden due to its association with heightened …

Malnutrition and the orthopaedic trauma patient: a systematic review of the literature

A Ernst, JM Wilson, J Ahn, M Shapiro… - Journal of orthopaedic …, 2018 - journals.lww.com
Objectives: To evaluate the available literature for associations between nutrition and
outcomes after operative treatment of long bone and long bone periarticular fractures. Data …

Calcium and vitamin-D deficiency marginally impairs fracture healing but aggravates posttraumatic bone loss in osteoporotic mice

V Fischer, M Haffner-Luntzer, K Prystaz… - Scientific reports, 2017 - nature.com
Calcium and vitamin-D (Ca/VitD) deficiency is a major risk factor for osteoporosis. It may also
contribute to the compromised bone healing frequently observed in osteoporotic patients …

Virgin coconut oil supplementation prevents bone loss in osteoporosis rat model

Z Hayatullina, N Muhammad… - Evidence‐Based …, 2012 - Wiley Online Library
Oxidative stress and free radicals have been implicated in the pathogenesis of osteoporosis.
Therefore, antioxidant compounds have the potential to be used in the prevention and …

Total flavonoids of Rhizoma Drynariae combined with calcium attenuate osteoporosis by reducing reactive oxygen species generation

P Mu, Y Hu, X Ma, J Shi… - Experimental and …, 2021 - spandidos-publications.com
In the present study, the effects of total flavonoids of Rhizoma Drynariae (TFRD) and calcium
carbonate (CaCO 3) on osteoporosis (OP) were assessed in a rat model of OP. For this …

Age dependence of systemic bone loss and recovery following femur fracture in mice

AJ Emami, CA Toupadakis, SM Telek… - Journal of Bone and …, 2019 - academic.oup.com
The most reliable predictor of future fracture risk is a previous fracture of any kind. The
etiology of this increased fracture risk is not fully known, but it is possible that fracture …

Inhibition of sclerostin by systemic treatment with sclerostin antibody enhances healing of proximal tibial defects in ovariectomized rats

MM McDonald, A Morse, K Mikulec… - Journal of …, 2012 - Wiley Online Library
Recent studies suggest a possible role for inhibitors of sclerostin such as sclerostin antibody
(Scl‐Ab) as an anabolic treatment for osteoporosis. Since Scl‐Ab has also been shown to …

Effects of α‐tocopherol on the early phase of osteoporotic fracture healing

AN Shuid, S Mohamad, N Muhammad… - Journal of …, 2011 - Wiley Online Library
Fracture healing is a complex process, which is more complicated if the bone is
osteoporotic. One of the vitamin E isomers, α‐tocopherol, has been found to prevent …

Rapid Determination and Quantification of Nutritional and Poisonous Metals in Vastly Consumed Ayurvedic Herbal Medicine (Rejuvenator Shilajit) by Humans Using …

RK Aldakheel, MA Gondal, HN Alsayed… - … Trace Element Research, 2022 - Springer
Abstract‏ Shilajit is used commonly as Ayurvedic medicine worldwide which is Rasayana
herbo-mineral substance and consumed to restore the energetic balance and to prevent …

The effects of alpha-tocopherol supplementation on fracture healing in a postmenopausal osteoporotic rat model

S Mohamad, AN Shuid, N Mohamed, FM Fadzilah… - Clinics, 2012 - SciELO Brasil
OBJECTIVE: Osteoporosis increases the risk of bone fractures and may impair fracture
healing. The aim of this study was to investigate whether alpha-tocopherol can improve the …