Glioma is the most frequent and aggressive type of brain neoplasm, being anaplastic astrocytoma (AA) and glioblastoma multiforme (GBM), its most malignant forms. The survival …
I Conti, G Varano, C Simioni, I Laface, D Milani… - Cells, 2020 - mdpi.com
microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the posttranscriptional level, inducing the degradation of the target mRNA or translational …
C Velásquez, S Mansouri, C Mora, F Nassiri… - Journal of …, 2019 - Wiley Online Library
The invasive capacity of GBM is one of the key tumoral features associated with treatment resistance, recurrence, and poor overall survival. The molecular machinery underlying GBM …
S Marino, G Menna, R Di Bonaventura, L Lisi… - Cancers, 2023 - mdpi.com
Simple Summary The new trends in the research on glioblastomas (GBMs) are focusing on understanding the crosstalk between proper neoplastic tissue and its microenvironment …
NA Viswan, US Bhalla - Current opinion in neurobiology, 2023 - Elsevier
If the genome defines the program for the operations of a cell, signaling networks execute it. These cascades of chemical, cell-biological, structural, and trafficking events span …
Osteosarcoma (OS) is an aggressive bone cancer for which survival has not improved over three decades. While biomaterials have been widely used to engineer 3D soft‐tissue tumor …
Motivation Mathematical models of biological processes altered in cancer are built using the knowledge of complex networks of signaling pathways, detailing the molecular regulations …
F Di Cintio, M Dal Bo, L Baboci, E De Mattia… - Frontiers in …, 2020 - frontiersin.org
Glioblastoma (GBM) is the most frequent and aggressive primary central nervous system tumor. Surgery followed by radiotherapy and chemotherapy with alkylating agents …
Chondroitin sulfate (CS) is a major component of the extracellular matrix found to be abnormally accumulated in several types of cancer tissues. Previous studies have indicated …