Mechanism of action of onabotulinumtoxinA in chronic migraine: a narrative review

R Burstein, AM Blumenfeld… - … : The Journal of …, 2020 - Wiley Online Library
Objective To review the literature on the mechanism of action of onabotulinumtoxinA in
chronic migraine. Background OnabotulinumtoxinA is a chronic migraine preventive …

Two-year outcomes of sacral neuromodulation versus onabotulinumtoxinA for refractory urgency urinary incontinence: a randomized trial

CL Amundsen, YM Komesu, C Chermansky… - European urology, 2018 - Elsevier
Background Urgency urinary incontinence (UUI) is a chronic condition for which sacral
neuromodulation (SNM)(InterStim/Medtronic) and onabotulinumtoxinA …

Evaluation and treatment of overactive bladder in women

R Raju, BJ Linder - Mayo Clinic Proceedings, 2020 - Elsevier
Overactive bladder (OAB) is a symptom complex that includes urinary urgency, frequency,
urgency incontinence, and nocturia. It is highly prevalent, affecting up to 12% of the adult …

Neutralizing Antibody Formation with OnabotulinumtoxinA (BOTOX®) Treatment from Global Registration Studies across Multiple Indications: A Meta-Analysis

J Jankovic, J Carruthers, M Naumann, P Ogilvie… - Toxins, 2023 - mdpi.com
Though the formation of neutralizing antibodies (NAbs) during treatment with botulinum
neurotoxin is rare, their presence may nonetheless affect the biological activity of botulinum …

Treatment of neurogenic detrusor overactivity and overactive bladder with Botox (onabotulinumtoxinA): Development, insights, and impact

V Nitti, C Haag-Molkenteller, M Kennelly, M Chancellor… - Medicine, 2023 - journals.lww.com
Neurogenic detrusor overactivity (NDO) is a complication of multiple sclerosis, spinal cord
injury (SCI), stroke, head injury, and other conditions characterized by damage to the upper …

OnabotulinumtoxinA (botulinum toxin type A) for the treatment of Japanese patients with overactive bladder and urinary incontinence: results of single‐dose treatment …

O Yokoyama, M Honda, T Yamanishi… - … Journal of Urology, 2020 - Wiley Online Library
Objective To evaluate the efficacy and safety of onabotulinumtoxinA (botulinum toxin type A)
100 U in patients with overactive bladder and urinary incontinence. Methods This was a …

Urinary retention in female OAB after intravesical Botox injection: who is really at risk?

P Miotla, R Cartwright, K Skorupska… - International …, 2017 - Springer
Introduction and hypothesis Intravesical onabotulinumtoxinA (Botox) injections are effective
for the treatment of idiopathic overactive bladder (OAB) symptoms. The aim of our study was …

Cost-effectiveness of sacral neuromodulation versus onabotulinumtoxinA for refractory urgency urinary incontinence: results of the ROSETTA randomized trial

HS Harvie, CL Amundsen, SJ Neuwahl… - The Journal of …, 2020 - auajournals.org
Purpose: Sacral neuromodulation and intradetrusor onabotulinumtoxinA injection are
therapies for refractory urgency urinary incontinence. Sacral neuromodulation involves …

Cost–effectiveness of overactive bladder treatments: from the US payer perspective

B Murray, SH Hessami, D Gultyaev… - Journal of …, 2019 - becarispublishing.com
Aim: To assess the cost–effectiveness of onabotulinumtoxinA (onabotA), implantable sacral
nerve stimulation devices, percutaneous tibial nerve stimulation, anticholinergic medications …

Botulinum toxin for treating overactive bladder in men: A systematic review

JC Truzzi, MC Lapitan, NC Truzzi… - Neurourology and …, 2022 - Wiley Online Library
Purpose We sought to systematically review the literature on the use of botulinum toxin (BTX‐
A) injections in the bladder to treat overactive bladder (OAB) in men. Materials and methods …