The orbitofrontal cortex and amygdala are involved in emotion and in motivation, but the
relationship between these functions performed by these brain structures is not clear. To …

The prefrontal cortex (PFC) plays a critical role in the generation and regulation of emotion.
However, we lack an integrative framework for understanding how different emotion-related …

Reversal learning paradigms are among the most widely used tests of cognitive flexibility
and have been used as assays, across species, for altered cognitive processes in a host of …

Economic choice behavior entails the computation and comparison of subjective values. A
central contribution of neuroeconomics has been to show that subjective values are …

Midbrain dopamine neurons are well known for their strong responses to rewards and their
critical role in positive motivation. It has become increasingly clear, however, that dopamine …

The orbitofrontal cortex (OFC) has long been associated with the flexible control of behavior
and concepts such as behavioral inhibition, self-control, and emotional regulation. These …

Traditionally the object of economic theory and experimental psychology, economic choice
recently became a lively research focus in systems neuroscience. Here I summarize the …

A range of emotional and motivation impairments have long been clinically documented in
people with schizophrenia, and there has been a resurgence of interest in understanding …

Recent evidence from neurophysiology and human functional neuroimaging has given rise
to the hypothesis that social, affective touch belongs to a distinct category of tactile …

Reinforcement learning provides both qualitative and quantitative frameworks for
understanding and modeling adaptive decision-making in the face of rewards and …