Interleukin 32, inflammation and cancer

JT Hong, DJ Son, CK Lee, DY Yoon, DH Lee… - Pharmacology & …, 2017 - Elsevier
Abstract Interleukin-32 (IL-32) is a novel cytokine involved in inflammation and cancer
development. IL-32 gene consists of eight small exons, and IL-32 mRNA has nine …

Genomic profiling of Sézary syndrome identifies alterations of key T cell signaling and differentiation genes

L Wang, X Ni, KR Covington, BY Yang, J Shiu… - Nature …, 2015 - nature.com
Sézary syndrome is a rare leukemic form of cutaneous T cell lymphoma characterized by
generalized redness, scaling, itching and increased numbers of circulating atypical T …

The interleukin-1α precursor is biologically active and is likely a key alarmin in the IL-1 family of cytokines

B Kim, Y Lee, E Kim, A Kwak, S Ryoo, SH Bae… - Frontiers in …, 2013 - frontiersin.org
Among the 11 members of the IL-1 family cytokines, the precursors of IL-1α, IL-1β, and IL-33
have relatively long N-terminal pro-sequences of approximately 100 amino acid residues …

IL-32, a novel proinflammatory cytokine in chronic obstructive pulmonary disease

F Calabrese, S Baraldo, E Bazzan… - American journal of …, 2008 - atsjournals.org
Rationale: Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory
disorder of the lung, yet the mechanisms that regulate this immune-inflammatory response …

IL-32 is expressed by human primary keratinocytes and modulates keratinocyte apoptosis in atopic dermatitis

N Meyer, M Zimmermann, S Bürgler, C Bassin… - Journal of Allergy and …, 2010 - Elsevier
BACKGROUND: Keratinocyte (KC) apoptosis is an important mechanism of eczema and
spongiosis in patients with atopic dermatitis (AD) and is mediated by IFN-γ, which is …

Structure and function of papiliocin with antimicrobial and anti-inflammatory activities isolated from the swallowtail butterfly, Papilio xuthus

JK Kim, E Lee, S Shin, K Jeong, JY Lee, SY Bae… - Journal of Biological …, 2011 - ASBMB
Papiliocin is a novel 37-residue cecropin-like peptide isolated recently from the swallowtail
butterfly, Papilio xuthus. With the aim of identifying a potent antimicrobial peptide, we tested …

Anti-inflammatory Activity of Rhamnetin and a Model of Its Binding to c-Jun NH2-Terminal Kinase 1 and p38 MAPK

HN Jnawali, E Lee, KW Jeong, A Shin… - Journal of natural …, 2014 - ACS Publications
Rhamnetin (1), a commonly occurring plant O-methylated flavonoid, possesses antioxidant
properties. To address the potential therapeutic efficacy of 1, its anti-inflammatory activity …

IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection

W Li, W Sun, L Liu, F Yang, Y Li, Y Chen… - The Journal of …, 2010 - journals.aai.org
Our previous studies with clinical data analysis have shown that the proinflammatory factor
IL-32 is activated in response to influenza virus infection. However, little is known about how …

Expression of IL-32 modulates NF-κB and p38 MAP kinase pathways in human esophageal cancer

NG Yousif, FG Al-Amran, N Hadi, J Lee, J Adrienne - Cytokine, 2013 - Elsevier
BACKGROUND: Esophageal cancer is the seventh leading cause of cancer death in males
in USA, and there is a strong link has been demonstrated between inflammation and …

Interleukin-32 expression in the pancreas

A Nishida, A Andoh, O Inatomi, Y Fujiyama - Journal of Biological Chemistry, 2009 - ASBMB
Interleukin (IL)-32 is a recently described proinflammatory cytokine characterized by the
induction of nuclear factor (NF)-κB activation. We studied IL-32 expression in human …