The medical literature describes numerous in vitro and in vivo wound‐healing models. The
selection of an animal model depends on a number of factors including availability, cost …

Background Oral phenytoin was first introduced as an antiseizure medication in 1937. Over
60 years investigators have shown an interest in how topical phenytoin may be used to …

Phenytoin (Ph), an antiepileptic drug, was reported to exhibit high wound healing activity.
However, its limited solubility, bioavailability, and inefficient distribution during topical …

Impaired healing of diabetic ulcers is one of the major complications of diabetic patients due
to high susceptibility to microbial infections, impaired lymphianogenesis, edema, and …

Split-thickness skin grafting (STSG) is a frequently used reconstructive technique but is
associated with a large variation in practice. The purposes of this article are to integrate and …

Oral phenytoin is used widely for the treatment of convulsive disorders and about half the
patients treated develop gingival overgrowth as a side effect. The apparent stimulatory effect …

Topical agents used for the enhancement of wound healing are designed to act locally and,
therefore, do not undergo classic systemic metabolic modification. This commentary reviews …

OBJECTIVE: To describe a patient with a massive Grade IV pressure ulcer that responded
rapidly to treatment with topical phenytoin and to review the literature supporting the use of …

Opiates remain the most common form of analgesic therapy in the burn patient today.
Because of increased opiate requirements, optimal relief of burn pain continues to be a …

The hip joint is one of the most surgically exposed joints in the body. The indications for
surgical exposure are numerous ranging from simple procedures such as arthrotomy for …