BP180 is critical in the autoimmunity of bullous pemphigoid

Y Liu, L Li, Y Xia - Frontiers in immunology, 2017 - frontiersin.org
Bullous pemphigoid (BP) is by far the most common autoimmune blistering dermatosis that
mainly occurs in the elderly. The BP180 is a transmembrane glycoprotein, which is highly …

Genetics of diffuse idiopathic skeletal hyperostosis and ossification of the spinal ligaments

H Kato, DT Braddock, N Ito - Current Osteoporosis Reports, 2023 - Springer
Abstract Purpose of Review The study aims to provide updated information on the genetic
factors associated with the diagnoses 'Diffuse Idiopathic Skeletal Hyperostosis'(DISH),' …

Ossification of the posterior longitudinal ligament of the cervical spine in 3161 patients: a CT-based study

T Fujimori, H Le, SS Hu, C Chin, M Pekmezci… - Spine, 2015 - journals.lww.com
Study Design. A cross-sectional study. Objective. To examine the prevalence of ossification
of the posterior longitudinal ligament (OPLL) and ossification of the nuchal ligament (ONL) of …

[HTML][HTML] The pathogenesis of ossification of the posterior longitudinal ligament

L Yan, R Gao, Y Liu, B He, S Lv, D Hao - Aging and disease, 2017 - ncbi.nlm.nih.gov
Ossification of the posterior longitudinal ligament (OPLL) is a multi-factorial disease
involving an ectopic bone formation of spinal ligaments. It affects 0.8-3.0% aging Asian and …

[HTML][HTML] Molecular pathophysiology of ossification of the posterior longitudinal ligament (OPLL)

DC Nam, HJ Lee, CJ Lee, SC Hwang - Biomolecules & …, 2019 - ncbi.nlm.nih.gov
Ossification of the posterior longitudinal ligament (OPLL) can be defined as an ectopic
ossification in the tissues of spinal ligament showing a hyperostotic condition. OPLL is …

A systematic review of classification systems for cervical ossification of the posterior longitudinal ligament

L Tetreault, H Nakashima, S Kato… - Global spine …, 2019 - journals.sagepub.com
Design: Systematic review. Objective: To conduct a systematic review to (1) summarize
various classification systems used to describe cervical ossification of the posterior …

Integrated microRNA-mRNA analyses reveal OPLL specific microRNA regulatory network using high-throughput sequencing

C Xu, Y Chen, H Zhang, Y Chen, X Shen, C Shi, Y Liu… - Scientific reports, 2016 - nature.com
Ossification of the posterior longitudinal ligament (OPLL) is a genetic disorder which
involves pathological heterotopic ossification of the spinal ligaments. Although studies have …

[HTML][HTML] Genetic odyssey to ossification of the posterior longitudinal ligament in the cervical spine: a systematic review

YI Won, CH Lee, WT Yuh, SW Kwon, CH Kim… - Neurospine, 2022 - ncbi.nlm.nih.gov
Despite numerous studies, the pathogenesis of ossification of the posterior longitudinal
ligament (OPLL) is still unclear. Previous genetic studies proposed variations in genes …

The long tail and rare disease research: the impact of next-generation sequencing for rare Mendelian disorders

T Shen, A Lee, C Shen, CJ Lin - Genetics research, 2015 - cambridge.org
There are an estimated 6000–8000 rare Mendelian diseases that collectively affect 30
million individuals in the United States. The low incidence and prevalence of these diseases …

The microRNA-10a/ID3/RUNX2 axis modulates the development of ossification of posterior longitudinal ligament

C Xu, H Zhang, W Gu, H Wu, Y Chen, W Zhou, B Sun… - Scientific reports, 2018 - nature.com
Ossification of the posterior longitudinal ligament (OPLL) presents as pathological
heterotopic ossification of the spinal ligaments. However, its underlying molecular …