Immunity of the greater wax moth Galleria mellonella

I Wojda - Insect science, 2017 - Wiley Online Library
Investigation of insect immune mechanisms provides important information concerning
innate immunity, which in many aspects is conserved in animals. This is one of the reasons …

Recent Advances in the Use of Galleria mellonella Model to Study Immune Responses against Human Pathogens

TC Pereira, PP De Barros, LRO Fugisaki, RD Rossoni… - Journal of Fungi, 2018 - mdpi.com
The use of invertebrates for in vivo studies in microbiology is well established in the scientific
community. Larvae of Galleria mellonella are a widely used model for studying …

Immune Response of Galleria mellonella against Human Fungal Pathogens

N Trevijano-Contador, O Zaragoza - Journal of Fungi, 2018 - mdpi.com
In many aspects, the immune response against pathogens in insects is similar to the innate
immunity in mammals. This has caused a strong interest in the scientific community for the …

Our current clinical understanding of Candida biofilms: where are we two decades on?

G Ramage, E Borghi, CF Rodrigues, R Kean… - APMIS, 2023 - Wiley Online Library
Clinically we have been aware of the concept of Candida biofilms for many decades, though
perhaps without the formal designation. Just over 20 years ago the subject emerged on the …

Fusarium, an Entomopathogen—A Myth or Reality?

L Sharma, G Marques - Pathogens, 2018 - mdpi.com
The Fusarium species has diverse ecological functions ranging from saprophytes,
endophytes, and animal and plant pathogens. Occasionally, they are isolated from dead and …

Microbiology's next top model: Galleria in the molecular age

H Dinh, L Semenec, SS Kumar, FL Short… - Pathogens and …, 2021 - academic.oup.com
Galleria mellonella has risen to fame as an invertebrate model organism given its ethical
advantages, low maintenance costs, rapid reproduction time, short life cycle, high number of …

Galleria mellonella: An invertebrate model to study pathogenicity in correctly defined fungal species

U Binder, E Maurer, C Lass-Flörl - Fungal Biology, 2016 - Elsevier
The high mortality rates and economic burden associated with fungal infections, plus the
emergence of fungal strains resistant to antifungal drugs, make it necessary to get a deeper …

Comparative analysis of secretome profiles of manganese (II)-oxidizing ascomycete fungi

CA Zeiner, SO Purvine, EM Zink, L Paša-Tolić… - PloS one, 2016 - journals.plos.org
Fungal secretomes contain a wide range of hydrolytic and oxidative enzymes, including
cellulases, hemicellulases, pectinases, and lignin-degrading accessory enzymes, that …

Establishment and validation of Galleria mellonella as a novel model organism to study Mycobacterium abscessus infection, pathogenesis, and treatment

M Meir, T Grosfeld, D Barkan - Antimicrobial agents and …, 2018 - Am Soc Microbiol
Treatment of Mycobacterium abscessus infections is extremely challenging due to its
intrinsic resistance to most antibiotics, and research of pathogenesis is limited due to a lack …

An integrative omics approach to unravel toxicity mechanisms of environmental chemicals: effects of a formulated herbicide

T Simões, SC Novais, T Natal-da-Luz, B Devreese… - Scientific reports, 2018 - nature.com
The use of integrative molecular approaches can aid in a comprehensive understanding of
the effects of toxicants at different levels of biological organization, also supporting risk …