The adenosine 5′-triphosphate-gated P2X4 receptor channel is a promising target in
neuroinflammatory disorders, but the ability to effectively target these receptors in models of …

P2X receptors (P2XRs) are adenosine 5′-triphosphate (ATP)–gated ion channels
comprising homomeric and heteromeric trimers of seven subtypes (P2X1–P2X7) that confer …

Mechanosensitive channel of large conductance (MscL) detects and responds to changes in
the pressure profile of cellular membranes and transduces the mechanical energy into …

P2X receptors are ATP-activated, non-specific cation channels involved in sensory
signalling, inflammation, and certain forms of pain. Investigations of agonist binding and …

Congenital long QT syndrome (LQTS) is characterized by a prolonged QT-interval on an
electrocardiogram (ECG). An abnormal prolongation in the QT-interval increases the risk for …

Natural products have been used traditionally for thousands of years to treat a wide variety
of ailments. The active compounds in Panax ginseng, the ginsenosides, have been shown …

P2X receptors are non-selective ATP-gated ion channels. ATP can act as a neurotransmitter
and activate P2X receptors, allowing the passage of small cations into the cell, causing …

Members of the parvalbumin (PV) family of calcium binding proteins are found in a variety of
vertebrates, where can they influence neural functions, muscle contraction and immune …