Natural phytochemicals as novel therapeutic strategies to prevent and treat Parkinson's disease: current knowledge and future perspectives

R Balakrishnan, S Azam, DY Cho… - Oxidative Medicine …, 2021 - Wiley Online Library
Parkinson's disease (PD) is the second‐most common neurodegenerative chronic disease
affecting both cognitive performance and motor functions in aged people. Yet despite the …

Dysregulation of the gut-brain axis, dysbiosis and influence of numerous factors on gut microbiota associated Parkinson's disease

G Kaur, T Behl, S Bungau, A Kumar… - Current …, 2021 - ingentaconnect.com
Background: Parkinson's disease (PD) has been one of the substantial social, medical
concerns and, burdens of the present time. PD is a gradually devastating neurodegenerative …

Molecular Mechanisms and Therapeutic Potential of α-and β-Asarone in the Treatment of Neurological Disorders

R Balakrishnan, DY Cho, IS Kim, SH Seol, DK Choi - Antioxidants, 2022 - mdpi.com
Neurological disorders are important causes of morbidity and mortality around the world.
The increasing prevalence of neurological disorders, associated with an aging population …

Exploring the focal role of LRRK2 kinase in Parkinson's disease

S Kumar, T Behl, A Sehgal, S Chigurupati… - … Science and Pollution …, 2022 - Springer
The major breakthroughs in our knowledge of how biology plays a role in Parkinson's
disease (PD) have opened up fresh avenues designed to know the pathogenesis of disease …

Potential benefits of phytochemicals from Azadirachta indica against neurological disorders

R Sandhir, M Khurana, NK Singhal - Neurochemistry international, 2021 - Elsevier
Azadirachta indica or Neem has been extensively used in the Indian traditional medical
system because of its broad range of medicinal properties. Neem contains many chemically …

Comparative potential of Simvastatin, Rosuvastatin and Fluvastatin against bacterial infection: an in silico and in vitro study

M Gupta, R Sharma, A Kumar - Oriental Pharmacy and Experimental …, 2019 - Springer
In the current investigation, we have compared the potential of statin drugs (Simvastatin,
Rosuvastatin and Fluvastatin) as potential anti-bacterial agent by conducting in silico, in vitro …

Pharmacological Potential of the Standardized Methanolic Extract of Prunus armeniaca L. in the Haloperidol‐Induced Parkinsonism Rat Model

U Saleem, L Hussain, F Shahid, F Anwar… - Evidence‐Based …, 2022 - Wiley Online Library
Parkinson's disease (PD) is a complex, age‐related neurodegenerative disease that causes
neuronal loss and dysfunction over time. An imbalance of redox potential of oxidative stress …

Natural chemical entities from Arisaema genus might be a promising break-through against Japanese encephalitis virus infection: a molecular docking and dynamics …

V Navyashree, K Kant, A Kumar - Journal of Biomolecular …, 2021 - Taylor & Francis
Japanese encephalitis virus (JEV) infection affects millions of population worldwide whose
incidence is increasing year by year and currently, no specific drugs are available for its …

Distinctive evidence involved in the role of endocannabinoid signalling in Parkinson's disease: a perspective on associated therapeutic interventions

T Behl, G Kaur, S Bungau, R Jhanji, A Kumar… - International Journal of …, 2020 - mdpi.com
Current pharmacotherapy of Parkinson's disease (PD) is symptomatic and palliative, with
levodopa/carbidopa therapy remaining the prime treatment, and nevertheless, being unable …

[HTML][HTML] Ethno pharmacology, phytochemical analysis, safety profile, prophylactic aspects, and therapeutic potential of Asarum europaeum L. in Unani medicine: An …

S Akhlaq, SA Ara, M Fazil, B Ahmad, U Akram… - Phytomedicine Plus, 2022 - Elsevier
Background A. europaeum is a well mentioned Unani herb, belonging to Aristolochiaceae
family and indigenous to the Eastern and Southern Europe. A. europaeum has traditionally …