Leprosy, a disease caused by the intracellular parasite Mycobacterium leprae or
Mycobacterium lepromatosis, has affected humans for more than 4,000 years and is a …

Across Europe, the genetics of the Chalcolithic/Bronze Age transition is increasingly
characterized in terms of an influx of Steppe-related ancestry. The effect of this major shift on …

The extent of the devastation of the Black Death pandemic (1346–1353) on European
populations is known from documentary sources and its bacterial source illuminated by …

JAK2V617F (dbSNP: rs77375493) is the most frequent and most-studied variant in BCR::
ABL1 negative myeloproliferative neoplasms and in the JAK2 gene. The present study …

Polymorphisms in cytokine genes can alter the production of these proteins and
consequently affect the immune response. The trihybrid heterogeneity of the Brazilian …

Leprosy is an infectious disease still highly prevalent in Brazil, having been detected around
27,863 new cases in 2019. Exposure to Mycobacterium leprae may not be sufficient to …

Prior to the advent of microbiology, infectious diseases had no known etiology and therefore
were often qualified as hereditary. With the advances in medicine, the key role of microbes …

Purpose: Earlier studies have shown that tumor necrosis factor (TNF)-308 G> A (rs1800629)
gene polymorphism is implicated in the susceptibility to leprosy, but results were …

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease
that is caused by a novel bunyavirus, SFTSV. We assessed whether the single nucleotide …

Leprosy has long been thought to have a strong genetic component, and so far, only
positional cloning and genomewide association studies have been used to study the genetic …