Canine oviductal exosomes improve oocyte development via EGFR/MAPK signaling pathway

SH Lee, HJ Oh, MJ Kim, BC Lee - Reproduction, 2020 - rep.bioscientifica.com
Oviduct cells produce a favorable environment for the development of gametes by
generating multiple growth factors. Particularly, in canine species, immature oocytes …

Melatonin-Nrf2 signaling activates peroxisomal activities in porcine cumulus cell-oocyte complexes

EH Kim, MR Ridlo, BC Lee, GA Kim - Antioxidants, 2020 - mdpi.com
Melatonin and Nrf2 signaling synergistically improve mammalian oocyte maturation and
embryonic development. Furthermore, previous studies have suggested an interplay …

Exosomes derived from oviduct cells mediate the EGFR/MAPK signaling pathway in cumulus cells

SH Lee, HJ Oh, MJ Kim, BC Lee - Journal of Cellular …, 2020 - Wiley Online Library
Current studies indicate that application of oviduct cells (OCs) in in vitro system create
microenvironment similar to the in vivo conditions by releasing multiple growth factors which …

Role of EGFR expressed on the granulosa cells in the pathogenesis of polycystic ovarian syndrome

JH Zhang, L Zhan, MY Zhao, JJ Wang, FF Xie… - Frontiers in …, 2022 - frontiersin.org
Polycystic ovarian syndrome (PCOS) is one of the most common endocrinological disorders
affecting between 6 to 20% of reproductive aged women. However, the etiology of PCOS is …

Human adipose-derived stem cells' paracrine factors in conditioned medium can enhance porcine oocyte maturation and subsequent embryo development

SH Lee - International Journal of Molecular Sciences, 2021 - mdpi.com
An essential requirement for the success of in vitro maturation (IVM) of the oocyte is to
provide an optimal microenvironment similar to in vivo conditions. Recently, somatic cell …

Follicular fluid exosomes regulate OVGP1 secretion in yak oviduct epithelial cells via autophagy in vitro

J Wang, Y Pan, M Wang, R Xu, X Han… - Journal of Cellular …, 2023 - Wiley Online Library
After mammalian ovulation, oocytes enter the oviduct, causing oocyte and oviduct changes.
Some studies have shown that follicular fluid exosomes (FEVs) play an important role in this …

The localization and expression of epidermal growth factor and epidermal growth factor receptor in bovine ovary during oestrous cycle

Y Luo, R Zhang, J Gao, Y Wang… - … in Domestic Animals, 2020 - Wiley Online Library
Epidermal growth factor (EGF) is one of the important regulatory factors of EGF family. EGF
has been indicated to effectively inhibit the apoptosis of follicular cells, to promote the …

Phytanic acid-derived peroxisomal lipid metabolism in porcine oocytes

EH Kim, GA Kim, A Taweechaipaisankul, MR Ridlo… - Theriogenology, 2020 - Elsevier
Lipid metabolism plays an important role in oocyte maturation. The peroxisome is the
fundamental mediator for this mechanism. In this study, we investigated the peroxisomal …

Melatonin restores the developmental competence of heat stressed porcine oocytes, and alters the expression of genes related to oocyte maturation

L Yang, Z Zhao, M Cui, L Zhang, Q Li - Animals, 2021 - mdpi.com
Simple Summary Melatonin improves the quality and in vitro maturation (IVM) of oocytes
under heat stress. Melatonin treatment counteracts the adverse effects induced by heat …

“Biological Adhesion” is a significantly regulated molecular process during long-term primary in vitro culture of oviductal epithelial cells (Oecs): A transcriptomic and …

J Budna-Tukan, A Światły-Błaszkiewicz… - International journal of …, 2019 - mdpi.com
Oviductal epithelial cells (OECs) actively produce stimulating and protecting factors, favoring
survival and viability of gametes and early embryos. The oviduct participates in the initial …