Malic acid derived from fossil resources is currently applied in the food and beverage
industries with a medium global production capacity. However, in the transition from a fossil …

Over the last few decades, increasing concerns regarding fossil fuel depletion and
excessive CO2 emissions have led to extensive fundamental studies and industrial trials …

Background The organic acid producer Aspergillus oryzae and Rhizopus delemar are able
to convert several alternative carbon sources to malic and fumaric acid. Thus, carbohydrate …

Malic acid, a four-carbon dicarboxylic acid, is widely used in the food, chemical and medical
industries. As an intermediate of the TCA cycle, malic acid is one of the most promising …

Abstract l-Malic acid has many uses in food, beverage, pharmaceutical, chemical and
medical industries. It can be produced by one-step fermentation, enzymatic transformation of …

Microbial fermentation was widely explored to produce malic acid. Previously, Aspergillus
niger has been successfully engineered, and a high titer of malic acid was achieved with …

Methanol has become an attractive substrate for biotechnological applications due to its
abundance and low-price. Chemicals production from methanol could alleviate the …

Abstract Malic acid (2-hydroxybutanedioic acid) is a four-carbon dicarboxylic acid, which has
attracted great interest due to its wide usage as a precursor of many industrially important …

Background Microbial malic acid production is currently not able to compete economically
with well-established chemical processes using fossil resources. The utilization of …

Synthesis gas (syngas) fermentation using acetogenic bacteria is an approach for
production of bulk chemicals like acetate, ethanol, butanol, or 2, 3-butandiol avoiding the …