Skeletal muscle tissue makes up approximately 40% of the total body mass in adult
mammals. Contractile muscle fibers building skeletal muscle tissue are coated by an …

The present study evaluated the role of interleukin (IL) 17 in multilineage commitment of
C2C12 myoblastic cells and investigated associated signaling pathways. The results …

We have examined the progression and regulation of myogenesis, cellular levels of IGFBP‐
4,‐5,‐6, and several extracellular matrix (ECM) proteins (fibronectin, integrin α5, β1 subunits …

Exogenous hyaluronan is known to alter muscle precursor cell proliferation, migration, and
differentiation, ultimately inhibiting myogenesis in vitro. The aim of the current study was to …

The purpose of the present study was to investigate the effect of interferon (IFN)-γ on the
transcriptomic profile of differentiating mouse C2C12 myogenic cells. Global gene …

The purpose of the study was to examine the mechanisms important for early myogenesis in
mouse C2C12 myogenic cells exposed to interleukin-1β. Cyclin A and cyclin B1 were …

The extracellular matrix (ECM) is considered a part of the myogenesis signaling mechanism.
We hypothesized that insulin-like growth factor-I (IGF-I) modifies ECM during differentiation …

Mutations in the gene encoding emerin (EMD) cause Emery–Dreifuss muscular dystrophy
(EDMD1), an inherited disorder characterized by progressive skeletal muscle wasting …

Alkaline phosphatase (AP) and other proteins add glycosylphosphatidylinositol (GPI) before
addressing to raft domains of the cell membrane. Our previous report showing an increased …

Mutations in the gene encoding emerin (EMD) cause Emery-Dreifuss muscular dystrophy
(EDMD1), an inherited disorder characterized by progressive skeletal muscle wasting …