Questioning rotary functionality in the bacterial flagellar system and proposing a murburn model for motility

KM Manoj, VD Jacob, M Kavdia… - Journal of …, 2023 - Taylor & Francis
Bacterial flagellar system (BFS) was the primary example of a purported 'rotary-
motor'functionality in a natural assembly. This mandates the translation of a circular motion …

Flagellar protein FliL: A many‐splendored thing

JD Partridge, RM Harshey - Molecular Microbiology, 2024 - Wiley Online Library
FliL is a bacterial flagellar protein demonstrated to associate with, and regulate ion flow
through, the stator complex in a diverse array of bacterial species. FliL is also implicated in …

Structural basis of the bacterial flagellar motor rotational switching

J Tan, L Zhang, X Zhou, S Han, Y Zhou, Y Zhu - Cell Research, 2024 - nature.com
The bacterial flagellar motor is a huge bidirectional rotary nanomachine that drives rotation
of the flagellum for bacterial motility. The cytoplasmic C ring of the flagellar motor functions …

FlbB forms a distinctive ring essential for periplasmic flagellar assembly and motility in Borrelia burgdorferi

JM Botting, MK Rahman, H Xu, J Yue, W Guo… - PLoS …, 2025 - journals.plos.org
Spirochetes are a widely existing group of bacteria with a distinct morphology. Some
spirochetes are important human pathogens that utilize periplasmic flagella to achieve …

Clostridioides difficile minimal nutrient requirements for flagellar motility

J Schwanbeck, I Oehmig, U Groß… - Frontiers in Microbiology, 2023 - frontiersin.org
As many gastro-intestinal pathogens, the majority of Clostridioides difficile strains express
flagella together with a complete chemotaxis system. The resulting swimming motility is …

[HTML][HTML] Structure and Dynamics of the Bacterial Flagellar Motor Complex

S Nakamura, T Minamino - Biomolecules, 2024 - mdpi.com
Many bacteria swim in liquids and move over solid surfaces by rotating flagella. The
bacterial flagellum is a supramolecular protein complex that is composed of about 30 …

Tuning the stator subunit of the flagellar motor with coiled‐coil engineering

P Ridone, DL Winter, MAB Baker - Protein Science, 2023 - Wiley Online Library
Many bacteria swim driven by an extracellular filament rotated by the bacterial flagellar
motor. This motor is powered by the stator complex, MotA5MotB2, an heptameric complex …

Flagellar motor remodeling during swarming requires FliL

JD Partridge, Y Dufour, YS Hwang… - Molecular …, 2023 - Wiley Online Library
FliL is an essential component of the flagellar machinery in some bacteria, but a conditional
one in others. The conditional role is for optimal swarming in some bacteria. During …

Light Control in Microbial Systems

Y Elahi, MAB Baker - International Journal of Molecular Sciences, 2024 - mdpi.com
Light is a key environmental component influencing many biological processes, particularly
in prokaryotes such as archaea and bacteria. Light control techniques have revolutionized …

Multi-parameter optimal control of F1-ATPase

WC Wareham, DA Sivak - arXiv preprint arXiv:2410.24122, 2024 - arxiv.org
Biological molecular machines convert free energy between different forms in cells, often at
high efficiency. Optimal control theory provides a framework to elucidate design principles …