L-carnitine and potential protective effects against ischemia-reperfusion injury in noncardiac organs: from experimental data to potential clinical applications

A Moghaddas, S Dashti-Khavidaki - Journal of Dietary …, 2018 - Taylor & Francis
The mechanism of ischemia-reperfusion (I/R) injury is complex and multifactorial. In this
condition, systemic event results in morbidity and mortality in several pathologies, including …

Carnitine metabolites and cognitive improvement in patients with schizophrenia treated with olanzapine: a prospective longitudinal study

L Zhao, H Liu, W Wang, Y Wang, M Xiu… - Frontiers in …, 2023 - frontiersin.org
Objective: Cognitive impairment is one of the core symptoms of schizophrenia, which is
stable and lifelong. L-carnitine has been shown to improve cognitive function and decrease …

Determination of major endogenous FAHFAs in healthy human circulation: the correlations with several circulating cardiovascular-related biomarkers and anti …

RA Dongoran, TJ Lin, A Byekyet, SC Tang, JH Yang… - Biomolecules, 2020 - mdpi.com
Fatty acid esters of hydroxy fatty acids (FAHFAs) are newly discovered long-chain fatty acids.
However, the major endogenous FAHFAs in healthy human circulation, their correlation with …

The anti-wasting effects of L-carnitine supplementation on cancer: experimental data and clinical studies

M Esfahani, S Sahafi, A Derakhshandeh… - Asia Pacific journal …, 2018 - search.informit.org
Background and Objectives: Cachexia is a paraneoplastic syndrome that affects the large
majority of patients with end-stage cancer. No known therapy exists to effectively overcome …

Clinical Evidence of Acetyl‐L‐Carnitine Efficacy in the Treatment of Acute Ischemic Stroke: A Pilot Clinical Trial

M Mazdeh, P Abolfathi, M Sabetghadam… - Oxidative medicine …, 2022 - Wiley Online Library
Background. This study was undertaken to evaluate the influence of oral Acetyl‐L‐carnitine
(ALC) in patients with acute ischemic stroke. Methods. Sixty‐nine cases with acute ischemic …

Effect of dietary l‐carnitine on growth performance and antioxidant response in Amur minnow (Phoxinus lagowskii Dybowskii)

Q Wang, S Luo, A Ghonimy, Y Chen, Z Guo… - Aquaculture …, 2019 - Wiley Online Library
Abstract l‐carnitine (LC) is required for transporting long‐chain fatty acids into the
mitochondria, where β‐oxidation takes place, and it works as an antioxidant molecule …

Protective effects of L-carnitine against beta-amyloid-induced memory impairment and anxiety-like behavior in a rat model of Alzheimer's disease

YJ Tork, E Naseri, HS Basir, A Komaki - European Journal of Pharmacology, 2024 - Elsevier
Abstract Alzheimer's disease (AD), the most common cause of dementia, leads to
neurodegeneration and cognitive decline. We investigated the therapeutic effects of L …

A comparison of L-carnitine and several cardiovascular-related biomarkers between healthy vegetarians and omnivores

TJ Lin, SC Tang, PY Liao, RA Dongoran, JH Yang… - Nutrition, 2019 - Elsevier
Objective A plant-based diet has been associated with a reduced risk of cardiovascular (CV)
diseases. This study aimed to determine the levels and correlations of CV-related …

Therapeutic potential of novel twin compounds containing tetramethylpyrazine and carnitine substructures in experimental ischemic stroke

Z Wang, Z Zhou, X Wei, M Wang… - Oxidative Medicine …, 2017 - Wiley Online Library
Although studies have seen dramatic advances in the understanding of the pathogenesis of
stroke such as oxidative stress, inflammation, excitotoxicity, calcium overload and apoptosis …

l-Carnitine improves follicular survival and function in ovarian grafts in the mouse

K Sanamiri, MS Mehranjani… - Reproduction …, 2022 - CSIRO Publishing
Context Ovarian tissue transplantation is performed to preserve fertility in patients
undergoing chemotherapy and radiotherapy. However, the ischemia-reperfusion injury …