Natural products and their bioactive compounds: neuroprotective potentials against neurodegenerative diseases

NS Mohd Sairazi… - … Based Complementary and …, 2020 - Wiley Online Library
In recent years, natural products, which originate from plants, animals, and fungi, together
with their bioactive compounds have been intensively explored and studied for their …

Multifunctional role of fucoidan, sulfated polysaccharides in human health and disease: A journey under the sea in pursuit of potent therapeutic agents

B Pradhan, S Patra, R Nayak, C Behera… - International Journal of …, 2020 - Elsevier
Fucoidan is a complex polysaccharide (molecular weight 10,000–100,000 Da) derived from
brown algae which comprises of L-fucose and sulfate groups have potential as therapeutic …

Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson's disease

S Sarkar, E Malovic, DS Harishchandra… - npj Parkinson's …, 2017 - nature.com
The NLRP3 inflammasome signaling pathway is a major contributor to the
neuroinflammatory process in the central nervous system. Oxidative stress and …

NADPH oxidases in Parkinson's disease: a systematic review

K Belarbi, E Cuvelier, A Destée, B Gressier… - Molecular …, 2017 - Springer
Parkinson's disease (PD) is a progressive movement neurodegenerative disease
associated with a loss of dopaminergic neurons in the substantia nigra of the brain …

The seaweed diet in prevention and treatment of the neurodegenerative diseases

L Pereira, A Valado - Marine Drugs, 2021 - mdpi.com
Edible marine algae are rich in bioactive compounds and are, therefore, a source of
bioavailable proteins, long chain polysaccharides that behave as low-calorie soluble fibers …

[图书][B] Therapeutic and nutritional uses of algae

L Pereira - 2018 - taylorfrancis.com
Algae have been used since ancient times as food, fodder, fertilizer and as source of
medicine. Nowadays seaweeds represent an unlimited source of the raw materials used in …

Balancing the functions of DNA extracellular traps in intracellular parasite infections: Implications for host defense, disease pathology and therapy

CC Koh, KJ Gollob, WO Dutra - Cell Death & Disease, 2023 - nature.com
The release of DNA to the extracellular milieu is a biological process referred to as etosis,
which is involved in both physiological and pathological functions. Although the release of …

[HTML][HTML] Fucoidans: Exploring its neuroprotective mechanisms and therapeutic applications in brain disorders

P Batista, SA Cunha, T Ribeiro, S Borges… - Trends in Food Science …, 2024 - Elsevier
Background Marine-derived natural products have been attracting attention from both the
food and pharmaceutical sectors due to their promising therapeutic attributes. Algae and …

Mitoapocynin treatment protects against neuroinflammation and dopaminergic neurodegeneration in a preclinical animal model of Parkinson's disease

A Ghosh, MR Langley, DS Harischandra… - Journal of Neuroimmune …, 2016 - Springer
Mitochondrial dysfunction, oxidative stress and neuroinflammation have been implicated as
key mediators contributing to the progressive degeneration of dopaminergic neurons in …

[HTML][HTML] Fucoidan protects dopaminergic neurons by enhancing the mitochondrial function in a rotenone-induced rat model of Parkinson's disease

L Zhang, J Hao, Y Zheng, R Su, Y Liao, X Gong… - Aging and …, 2018 - ncbi.nlm.nih.gov
The mitochondrion is susceptible to neurodegenerative disorders such as Parkinson's
disease (PD). Mitochondrial dysfunction has been considered to play an important role in …