In the last two decades, metal-catalyzed controlled radical polymerization (CRP), or atom
transfer radical polymerization (ATRP) has become a ubiquitous tool for the facile synthesis …

Revised and updated, Chemical Reagents for Protein Modification, Third Edition is an
encyclopedic work describing the many approaches to the site-specific modification of …

Precise determination of disulfide linkages between cysteine (Cys) residues in proteins is
essential in the determination of protein structure. Therefore, a reliable automated method …

Describing the organization of substrates and substrate analogues in the active site of
cysteine dioxygenase identifies potential intermediates in this critical yet poorly understood …

In contrast to other vertebrate hemoglobins (Hbs) whose high intrinsic O2 affinities are
reduced by red cell allosteric effectors (mainly protons, CO2, organic phosphates, and …

Abstract α1‐Microglobulin (α1m) is a 26 kDa plasma and tissue protein belonging to the
lipocalin protein family. Previous investigations indicate that the protein interacts with heme …

Nitrophorins represent a unique class of heme proteins that are able to perform the delicate
transportation and release of the free-radical gaseous messenger nitric oxide (NO) in a pH …

NO is an important signaling molecule in human tissue. However, the mechanisms by which
this molecule is controlled and directed are currently little understood. Nitrophorins (NPs) …

The factors leading to the breakage of the proximal iron–histidine bond in the ferroheme
protein soluble guanylate cyclase (sGC) are still a matter of debate. This event is a key …

Nitric oxide signals through activation of soluble guanylyl cyclase (sGC), a heme-containing
heterodimer. NO binds to the heme domain located in the N-terminal part of the β subunit of …