Momordica charantia, a Nutraceutical Approach for Inflammatory Related Diseases

M Bortolotti, D Mercatelli, L Polito - Frontiers in pharmacology, 2019 - frontiersin.org
Momordica charantia, commonly called bitter melon, is a plant belonging to Cucurbitaceae
family known for centuries for its pharmacological activities, and nutritional properties. Due …

Promise of bitter melon (Momordica charantia) bioactives in cancer prevention and therapy

K Raina, D Kumar, R Agarwal - Seminars in cancer biology, 2016 - Elsevier
Recently, there is a paradigm shift that the whole food-derived components are not 'idle
bystanders' but actively participate in modulating aberrant metabolic and signaling pathways …

A detailed review on the phytochemical profiles and anti-diabetic mechanisms of Momordica charantia

SF Oyelere, OH Ajayi, TE Ayoade, GBS Pereira… - Heliyon, 2022 - cell.com
Diabetes mellitus is the most well-known endocrine dilemma suffered by hundreds of million
people globally, with an annual mortality of more than one million people. This high mortality …

Triterpenoids

RA Hill, JD Connolly - Natural Product Reports, 2020 - pubs.rsc.org
Covering 2015. Previous review: Nat. Prod. Rep., 2018, 35, 1294–1329 This review covers
the isolation and structure determination of triterpenoids reported during 2015 including …

The triterpenoids of the bitter gourd (Momordica Charantia) and their pharmacological activities: A review

L Sun, X Zhang, L Dong, C Zhang, P Guo… - Journal of Food …, 2021 - Elsevier
The bitter gourd (Momordica charantia L.) is a world-famous medical vegetable involved in
multiple pharmacological activities especially known for its lipid-and glucose-lowering …

Cucurbitane-type compounds from Momordica charantia: Isolation, in vitro antidiabetic, anti-inflammatory activities and in silico modeling approaches

SR Shivanagoudra, WH Perera, JL Perez, G Athrey… - Bioorganic …, 2019 - Elsevier
Momordica charantia L., commonly known as bitter melon, belongs to the Cucurbitaceae
family. Various in vitro and in vivo studies have indicated that extracts of bitter melons have …

Anti-Inflammatory, Antidiabetic Properties and In Silico Modeling of Cucurbitane-Type Triterpene Glycosides from Fruits of an Indian Cultivar of Momordica charantia …

WH Perera, SR Shivanagoudra, JL Pérez, DM Kim… - Molecules, 2021 - mdpi.com
Diabetes mellitus is a chronic disease and one of the fastest-growing health challenges of
the last decades. Studies have shown that chronic low-grade inflammation and activation of …

Phytochemical profile and biological activities of Momordica charantia L.(Cucurbitaceae): A review

MS de Oliveira, WA da Costa… - African Journal of …, 2018 - academicjournals.org
This study discusses the bioactive composition, supercritical fluid extraction and biological
activities of Momordica charantia L. from the last five years. Numerous compounds that have …

In vitro and in silico elucidation of antidiabetic and anti-inflammatory activities of bioactive compounds from Momordica charantia L.

SR Shivanagoudra, WH Perera, JL Perez… - Bioorganic & Medicinal …, 2019 - Elsevier
Bitter melon (Momordica charantia) has been used to manage diabetes and related
conditions in various parts of the world. In the present study, ten compounds were isolated …

A triterpenoid from wild bitter gourd inhibits breast cancer cells

LY Bai, CF Chiu, PC Chu, WY Lin, SJ Chiu, JR Weng - Scientific reports, 2016 - nature.com
The antitumor activity of 3β, 7β, 25-trihydroxycucurbita-5, 23 (E)-dien-19-al (TCD), a
triterpenoid isolated from wild bitter gourd, in breast cancer cells was investigated. TCD …