Molecular mechanisms of acrolein toxicity: relevance to human disease

A Moghe, S Ghare, B Lamoreau… - Toxicological …, 2015 - academic.oup.com
Acrolein, a highly reactive unsaturated aldehyde, is a ubiquitous environmental pollutant
and its potential as a serious environmental health threat is beginning to be recognized …

Molecular mechanisms and pathophysiological significance of eryptosis

SA Alghareeb, MA Alfhili, S Fatima - International Journal of Molecular …, 2023 - mdpi.com
Despite lacking the central apoptotic machinery, senescent or damaged RBCs can undergo
an unusual apoptosis-like cell death, termed eryptosis. This premature death can be caused …

[PDF][PDF] A comprehensive review on eryptosis

E Pretorius, JN du Plooy, J Bester - Cellular Physiology and …, 2016 - karger.com
Erythrocytes (RBCs) are extremely sensitive cells, and although they do not have nuclei and
mitochondria, are important health indicators. This is particularly true because, during …

Mechanisms and pathophysiological significance of eryptosis, the suicidal erythrocyte death

E Lang, F Lang - Seminars in cell & developmental biology, 2015 - Elsevier
Eryptosis, the suicidal erythrocyte death characterized by cell shrinkage and cell membrane
scrambling, is stimulated by Ca 2+ entry through Ca 2+-permeable, PGE 2-activated cation …

Triggers, inhibitors, mechanisms, and significance of eryptosis: the suicidal erythrocyte death

E Lang, F Lang - BioMed research international, 2015 - Wiley Online Library
Suicidal erythrocyte death or eryptosis is characterized by erythrocyte shrinkage, cell
membrane blebbing, and cell membrane scrambling with phosphatidylserine translocation …

Oxidative stress and suicidal erythrocyte death

F Lang, M Abed, E Lang, M Föller - Antioxidants & redox signaling, 2014 - liebertpub.com
Significance: Eryptosis, the suicidal erythrocyte death, is characterized by cell shrinkage,
membrane blebbing, and phosphatidylserine translocation to the outer membrane leaflet …

Uremic toxins affect erythropoiesis during the course of chronic kidney disease: a review

E Hamza, L Metzinger, V Metzinger-Le Meuth - Cells, 2020 - mdpi.com
Chronic kidney disease (CKD) is a global health problem characterized by progressive
kidney failure due to uremic toxicity and the complications that arise from it. Anemia …

Pathophysiology of red blood cell dysfunction in diabetes and its complications

A Williams, R Bissinger, H Shamaa, S Patel, L Bourne… - Pathophysiology, 2023 - mdpi.com
Diabetes Mellitus (DM) is a complex metabolic disorder associated with multiple
microvascular complications leading to nephropathy, retinopathy, and neuropathy. Mounting …

Suicidal erythrocyte death in end-stage renal disease

M Abed, F Artunc, K Alzoubi, S Honisch… - Journal of molecular …, 2014 - Springer
Anemia in end-stage renal disease (ESRD) results mainly from erythropoietin and iron
deficiency. Anemia could be confounded, however, by accelerated clearance of circulating …

Effect of saponin on erythrocytes

R Bissinger, P Modicano, K Alzoubi, S Honisch… - International journal of …, 2014 - Springer
Saponins, naturally occurring glycosides and triterpene glycosides in plants, are considered
useful in the prophylaxis and treatment of several disorders, including malignancy. The …