The advent of clustered regularly interspaced short palindromic repeat (CRISPR) genome
editing, coupled with advances in computing and imaging capabilities, has initiated a new …

Plants cannot move, so they must endure abiotic stresses such as drought, salinity and
extreme temperatures. These stressors greatly limit the distribution of plants, alter their …

Feeding the ever-growing population is a major challenge, especially in light of rapidly
changing climate conditions. Genome editing is set to revolutionize plant breeding and …

Over the past decade, genomics-assisted breeding (GAB) has been instrumental in
harnessing the potential of modern genome resources and characterizing and exploiting …

Prime editing is a versatile genome-editing technology, but it suffers from low editing
efficiency. In the present study, we introduce optimized prime editors with substantially …

Gene therapy would benefit from a miniature CRISPR system that fits into the small adeno-
associated virus (AAV) genome and has high cleavage activity and specificity in eukaryotic …

Global climate variations induce extreme temperatures and significantly decrease crop
production, leading to food insecurity worldwide. Temperature extremes (mainly cold stress …

Crop wild relatives (CWRs) have provided breeders with several'game-changing'traits or
genes that have boosted crop resilience and global agricultural production. Advances in …

The discovery and application of genome editing introduced a new era of plant breeding by
giving researchers efficient tools for the precise engineering of crop genomes. Here we …

Global climate changes cause extreme temperatures and a significant reduction in crop
production, leading to food insecurity worldwide. Temperature extremes (including both heat …